u/ChattoGamer

Hi everyone. I’ve had one of the most complex, chaotic medical histories my doctors have ever seen, spanning from a structural heart defect at birth to an incredibly hyper-reactive immune system. I wanted to map out my timeline here to see if anyone else has experienced this exact cluster of autoimmune, gynecological, and severe mast cell/allergic responses.

Here is the timeline of how my "elite guards" (my hyper-reactive immune system) have fought my entire life.

🧬 Paternal Family Health History (My Genetic Map)

Advanced Cancers: Uterine Cancer (Stage 4), Colon Cancer (Stage 4), and Stomach Cancer (Stage 4).

Neurological & Structural: Brain tumor, Ankylosing Spondylitis (active in my father).

Metabolic & Cardiovascular: Type 2 Diabetes, severe heart problems.

Immune System: Severe drug, food, and environmental allergies.

👶 Infancy: The Critical Beginnings

Day 1: Born with a congenital heart defect (muscle layer failed to close).

0–2 Months: Repeatedly hospitalized for severe infections; standard antibiotics failed to work.

2 Months Old: Rushed to the ER after turning blue (cyanosis). Doctors gave me 4 months to live due to the unclosed heart defect.

6 Months–5 Years: Defied the diagnosis completely. My heart muscle naturally closed, and I grew up as a highly energetic, healthy child.

🧒 Childhood & Teens: Autoimmune & Atopic Flares

6 Years Old: Suddenly lost the ability to walk due to severe for a day, mysterious joint pain. This is a painful memory where I was crying and didn't know what to do.

9 or 10 Years Old: Diagnosed with severe lactose intolerance. (Decades later, my gut would completely surprise me).

6–14 Years: Frequent hospital check-ups. Doctors dismissed my pain, claiming I was "pretending" to skip school. Experienced chronic, on-and-off eczema in the groin area.

14 Years Old: Tested positive for HLA-B27 (genetic marker strongly linked to Ankylosing Spondylitis, which my father also has).

Underwent physical rehab until age 16.

19 Years Old: Diagnosed with GERD and IBS. Doctors blamed stress, even though I was happily studying Fine Arts with zero stress. Eczema migrated to my right elbow pit.

👩 Early 20s: Environmental & Occupational Triggers

20–21 Years: Severe ankle swelling left doctors baffled. A holistic doctor identified a pork allergy. Transitioned to a vegetarian diet for a year before reintroducing clean proteins.

21 Years Old (2012): Working at an animation studio; suddenly lost the ability to walk again. Required intense physical rehabilitation and had to quit my job.

2014: Worked as a sculptor. Developed massive red hives across my stomach due to toxic chemical exposure from the art materials, forcing me to quit.

🚨 2016–2018: The Anaphylactic Era & "Gout"

2016: First major anaphylaxis. I ate chicken cooked in lard at a restaurant. Airways swelled, causing severe breathing distress for 45 minutes.

Later that year: A waiter mistakenly served me vodka instead of water. One sip caused the right side of my brain to go completely numb.

First Allergist Visit: Diagnosed with mild asthma and environmental allergies; prescribed antihistamines and an inhaler.

2017: Developed butterfly rashes (lupus-like) and a severely swollen left foot sole, diagnosed as gout. Relegated to a wheelchair and crutches for 6 months. All Lupus (SLE) panels have remained strictly negative to this date. Chronic constipation began. Eczema on my neck and right elbow pit turned black and spread. Had a severe UTI requiring IV antibiotics. Blood tests also revealed low Vitamin D levels.

2018: Drank Bignay wine and suffered an immediate reaction—severe heart palpitations, and my skin turned black.

📉 2023–2024: Sciatica & Gynecological Crisis

2023–2024: Hit with severe, debilitating sciatica that left me unable to walk for months. Developed a completely stiff neck; X-rays revealed a straight neck bone (loss of cervical lordosis) requiring a neck brace.

The Eczema Breakthrough: After 27 years, Eczema finally cleared after I started making my own chemical-free handmade soaps which turned into a business.).

July–December 2024: Sudden onset of severe menorrhagia (heavy bleeding). Bleeding through 4 overnight pads a day. By December, I endured a continuous 15-day cycle with agonizing cramps, forcing me to close my soap business.

Dec 18, 2024: Went to OB-GYN clinic for an ultrasound. Revealed 6 multiple uterine fibroids; scheduled for an operation.

🏥 2025: The Surgical Crisis & The "Missing" Fibroids

January 2025: Battling a flu/cough before surgery. Was prescribed high-dosage oral amoxicillin (1g) but it completely failed to work. After a week, my period hit, and the OB-GYN injected me with Tranexamic Acid (TXA) for the bleeding, triggering a severe reaction. Because the antibiotics failed, she suggested drinking turmeric tea.

The TXA Allergy Timeline:

Jan 11, 2025: Sensitization Dose Type IV Delayed skin reaction (palm-sized swelling).

Jan 28, 2025 (Surgery Day): Challenge Dose Type I Immediate Systemic Anaphylaxis. My heart crashed (acute bradycardia) and my lungs collapsed on the operating table before the incision could even be made.

🏥 The Surgical Crisis & Lifelong Guardianship (January 28, 2025)

The Lifelong Bond: The 1st OB-GYN (the Surgeon) is the dearest friend of the patient's mother. She delivered the patient at birth, diagnosed her congenital heart defect ("pink baby"), and used her immense network at Chinese General Hospital to find the specialists who saved the patient's life after a 4-month mortality prognosis.

The OR Panic of Love: On January 28, 2025, the Surgeon faced a nightmare scenario: the patient suffered Stage 4 Anaphylactic Shock from the TXA and Fentanyl, and an unexpected 8cm giant fibroid was discovered. Without TXA to safely stop a hemorrhage, the Surgeon faced the terrifying prospect of losing the baby she had delivered decades prior. In a state of intense, protective panic, she said: "She was expecting to see only 6 but never expected the 8cm. If she needs a hysterectomy then beat it, come what may." She cut out 8 masses, leaving the inner uterus and the 8cm giant untouched purely to get the patient off the table alive.

The Empty Abstract & Initial Clinic Confusion: While driven by protective panic, the surgeon and anesthesiologist omitted the chaotic details of the pre-op systemic collapse from the patient's official medical abstract.This medical omission left the patient with a completely "empty" report. Consequently, during their very first meeting, the current Allergist and the 4th OB-GYN were deeply confused, trying to treat a high-stakes patient without any official record of the operating table crisis.

The Ward Panic & The Cover-Up: While I was recovering, my family suddenly went completely silent about the details of the operation. A week after my surgery, my cousin (a CGH nurse) went down to snoop in the OB ward to find out what had actually happened. The moment she asked about me, the floor nurses panicked all over again. They gasped and told her, "Oh, that's your cousin? We were preparing to intubate her right there." This confirmed the patient had fully crashed in the OR, despite the original surgeon and anesthesiologist omitting the chaotic details from the basic medical abstract to protect themselves.

The Post-Op Symptoms and Follow-Up Ultrasound:

March–June 2025: Bled continuously for 4 months post-surgery. My 3rd OB-GYN told me to stop contraceptive pills for a month (June to July). In August 2025, I started taking Trust Pill, which keeps my period regular to this date.

May 2025: My first post-op ultrasound revealed 8 remaining fibroids (the microscopic seeds left behind from the 2025 emergency surgery that grew rapidly due to shifting blood supply).

July–November 2025: Suffered a massive, full-body musculoskeletal flare-up (soles, left knee, left wrist, neck, and pelvic sciatica). I was physically moving slower than my father who has active Ankylosing Spondylitis. (Note: I later discovered that hidden corn consumption was the primary culprit behind this severe mobility flare).

The Merry-Go-Round of Medical Panic Post-Op:

1st OB-GYN (The Surgeon): Managed my continuous bleeding until May 2025. When my mom demanded to know why the 8cm fibroid was left behind, she snapped: "Aren't you glad your daughter is alive and standing in front of us?" She admitted that in her entire career, she had never encountered a patient like me, causing her to panic in the OR. She abruptly took a vacation to the US, forcing us to find a new doctor.

2nd OB-GYN: Directly told me it was a literal miracle I survived that operating table, warned me that any future major surgery could be fatal, and told me to stop looking for a surgical cure and just try to live my life.

Breast Oncologist: Was baffled by why the original team relied so heavily on TXA instead of standard blood transfusions. Admitted he had never encountered a case like mine in his entire career and referred me out.

3rd OB-GYN (Professor at UP Manila / PGH): Sat me down, looked at my history, and begged me to see a specialist, stating my case was completely outside her forte. When I asked about a hysterectomy, she looked at me and said "NO" 15 consecutive times, telling me the surgical risk was far too high.

🩺 2026: The Master Puzzle Solved

January–March 2026: Comprehensive testing finally gave me answers. Got a proper diagnosis for my food, environmental, and drug allergies, as well as Allergic Rhinitis.

The 4th OB-GYN & Protecting the Friendship: The 1st and 4th OB-GYNs are known best friends in real life. Because of this deep personal bond, the patient was initially highly hesitant to become a patient of the 4th OB-GYN (the Department Head), deeply wishing to protect their friendship and avoid causing professional conflict.

The Diplomatic Resolution: The patient's brilliant Allergist acted as the ultimate bridge. By rigorously confronting the anesthesiologist and isolating the TXA and Fentanyl anaphylaxis with scientific proof, the Allergist filled in the empty report. The 4th OB-GYN can fully prioritize the patient's rare case with immense integrity, and out of profound respect for the Allergist's clinical data, she physically stands up during consultations when her name is mentioned. The hospital network remains completely unified in friendship and protection ("Here in CGH we are friends. We help the patients first").

The Confrontation & Vindication:

Despite the friendships and hospital politics, the truth won. I found an extraordinary, fearless Allergist. When my allergist reviewed what happened, she personally confronted the operating room anesthesiologist, refusing to let them hide the pre-op crash.

My Allergist and my 4th OB-GYN launched a rigorous clinical investigation. They officially, scientifically verified that the operating table crash was Stage 4 Anaphylactic Shock, successfully isolating the culprits as Tranexamic Acid (TXA) and Fentanyl. The medical proof was so undeniable that the 4th OB-GYN had to choose professional integrity over her best friend's cover-up. Now, whenever I visit the 4th OB-GYN's clinic, she might forget a standard profile—but the absolute second my Allergist's name is mentioned, she instantly remembers my case and physically stands up out of deep professional respect. My allergist beautifully handled the hospital friction, telling me: "We have to move forward and forget the past. Here, we are friends. We help the patients first.”

The Awake Colonoscopy: I underwent a full colonoscopy with absolutely zero anesthesia due to my severe anesthesia/drug allergies. Thanks to a remarkably high pain tolerance, I made it through the procedure completely awake, and the colonoscopy was cleared.

Case Number 6:

When I asked my allergist how many patients she has ever seen like me, she counted them out loud. She has only ever had 5 cases like this in her entire career—I am case number 6. She told me she has only ever had one other patient in her life with a full "one-page bond paper list of severe allergies." She laughed and said I might be the second. I didn't laugh; I just frowned. It made me realize just how incredibly rare and complex my body truly is.

The Underlying Diagnosis:

Finally diagnosed with Adenomyosis (which explained the historic 4-month bleeding streak).

The Intervention: Started a strict Carnivore (pure beef and salt) diet in March 2026, after 16 years of being a vegetarian. This act alone has completely silenced my adenomyosis, stopped my bleeding, and keeps my remaining 8 fibroids completely quiet and inflammation-free.

May 2026: Suffered 3 distinct anaphylactic episodes this month alone due to acute exposure to cats, dogs, and cat litter.

The Lactose Miracle: After a lifetime of avoiding dairy due to my childhood diagnosis at age 9, my gut has healed so deeply on this baseline that I can now drink pure milk with absolutely zero stomach or digestive issues.

The Sleep Restoration: By introducing Magnesium Glycinate on May 7, 2025, I successfully repaired my nervous system, shifting from a broken 3 to 4 hours of sleep to a consistent 7 to 8 hours of deep, restful sleep every single night.

🚫 My Comprehensive Allergy & Reactivity Blueprint

Through a lifetime of trial and error (and recent hypersensitivity testing), my immune system reacts violently to the following:

🥩 Food & Environmental Triggers

* Pork: Airway nearly closes; cooking smells clog my nose.

* Soy Sauce: Massive butterfly rashes and large hives on upper buttocks/palms.

* MSG: Instant, severe headaches.

* Corn: Severe, immediate joint inflammation (The primary trigger behind my 5-month paralysis/musculoskeletal crisis in late 2025).

* Tuna & Bangus: Dry mouth and painful, raw gums.

* Mango: Causes distinct black spots to form on my face.

* Short Mackerel (Alumahan): Destroys my face with a swollen right eyebag.

* Lumpiang Sariwa( Vegetable wrapped): Clogged nose and severe neck pain.

* Beef Dimsum (with soup inside): Severe frontal headache.

* Beef Kimbap (with fish cake): Intense joint and muscle pain stretching from my hip to above the knee.

* Tomato: Sharp pain between the back of my head and neck.

* Maca Root Powder: Red, painful (but not swollen) gums, and 4 days of painfully dry, peeling, and wounded nostrils.

* Polvoron: Slight tightening of the neck and airway.

* Processed Cheese (Mozzarella, Cheddar, Parmesan): Severe stomach ache and vomiting.

* Boiled Saba Banana: Swells my throat, making it difficult to swallow for 12 hours.

* Chicken Masala: Instant phlegm accumulation and a continuous 1-hour coughing fit.

* Cats, Dogs, & Cat Litter/Poo: Massive asthma/coughing fits with thick phlegm, throat tightening, voice loss, and an immediate spike in blood pressure (125/75, 98 bpm from a baseline of 99/60).

* 1st Floor Cat Dander Air: Triggers an immediate, acute choking sensation, a constant need to clear my throat, and makes it incredibly difficult to speak straight. (I have to stay strictly on the 2nd floor to breathe safely).

💊 Severe Drug Allergies

* Tranexamic Acid (TXA / Hemostan): Stage 4 Anaphylactic Shock.

* Amoxicillin / Penicillin Group: Completely ineffective against respiratory issues.

* Paracetamol: Triggers intense headaches.

* Glucosamine: Causes bright red, flushed cheeks.

* Melatonin: Causes severe, immediate constipation.

* Propofol (Anesthesia Skin Test): Diluted test caused localized bruising and pain after 6 hours, followed by hives at 12 hours (bruising lasted 4 days). Concentrated test caused immediate pain at 6 hours, hives at 12 hours, and intense full-body pain after 24 hours.

* Fentanyl (Anesthesia Skin Test): Diluted test caused hives after 12 hours. Concentrated test caused deep bruising after 24 hours that lasted for 4 days.

* Zykast (Cetirizine + Montelukast): Induced severe, paradoxical neuropsychiatric adverse events (intense, uncontrollable outbursts of anger/rage while alone). Discontinued permanently in March 2026 following the colonoscopy procedure.

🧠 Where I Am Today

My immune system behaves in a state of neuro-immune hyper-vigilance, severe atopy, and mast cell hypersensitivity. High cortisol (like my phobia of heights or intense physical stress) acts as an immediate trigger, packing my "histamine bucket" to the brim and causing weeks-long lethargy/crashes.

By utilizing a pure beef baseline diet, working with an incredibly meticulous new OB-GYN and Allergist team, and fiercely protecting my nervous system from unnecessary stress, I am finally stable, pain-free, and resting well.

However, I have found my unique remedies. For the last two weeks, I have been drinking a daily turmeric, ginger, and cinnamon tea blend which has acted as a powerful natural anti-inflammatory for me—completely flushing out my severe water retention and systemic swelling, allowing me to finally fit back into my pre-myomectomy clothes.

My allergist keeps me relaxed by reminding me that her only other "one-page allergy list" patient has been successfully managed by her for over 15 years and is living safely into old age.

💊 My Targeted Supplement Regimen

Because my body is highly sensitive, I have carefully selected specific supplements to support my organs, nerves, and hormonal health:

For Fibroids & Hormonal Balance:

* DIM (Diindolylmethane) & N-Acetyl Cysteine (NAC): Taken specifically to help metabolize estrogen, regulate hormones, and target the remaining uterine fibroids.

For Sleep & Nervous System Support:

* Magnesium Glycinate: Used to repair my sleep cycle. Before taking this, I could only sleep a broken 3 to 4 hours a night.

* Vitamin B12: Dedicated to soothing and repairing my sciatic nerve pain.

* Vitamin D3: Continued protocol since my low diagnosis in 2017 to support overall immune function.

For Liver & Vascular Health:

* Milk Thistle: Taken to support and detoxify my sluggish liver, helping it clear out old hormones and histamines.

* Vitamin K2: Targeted at healing my spider veins, effectively changing them from an angry blue to a healing red.

Has anyone else with the HLA-B27 gene experienced this level of extreme Mast Cell / Allergic hyper-reactivity and gynecological chaos? Would love to hear your thoughts.