r/PCOSonGLP

Hello! I’m F21 and have been “diagnosed” with PCOS for as long as I can remember. Had amenorrhea and then went on bc for a year. hated it. treated a symptom not the cause. I really want to get nutrition, lifestyle, medications, supplements, etc under control. But i’m so confused and so so tired of all the conflicting info and band aid solutions so i’d love some advice if anyone is able to help 😭
If anyone has a good all in one resource, that would be awesome.

- Naturally, in PCOS fashion, I have the worst PCOS belly and am overweight. Nothing ever works, did Ozempic for a bit. Not very regular with it though. I didn’t find it very fruitful though. Didn’t help with my PCOS symptoms but it did help me lose a bit of weight. Was looking to start Mounjaro (would have to pay much more), any advice when starting out? How should I track or best build habits? What can I do now to make titrating down easier? Has the GLP been worth it? Esp. considering the money

- What are the go to supplements? Why?? 😭

- Is hair growth suppression medication worth it for hirusitism?

- What are the staple foods to avoid? Please meal prep tips or foods that are easy/cheap to make since i’m a college student and meal prepping is genuinely the death of me i don’t each much at all :////

- Why is strength training such a must? How do I do it in the “right” way? What should I train? How often?? I used to strength train but don’t anymore because I thought it wouldn’t help and make me lose weight slower… Also hard to see results for something so long term. Any tips??

- Any other tips or resources is exceptionally appreciated..

Btw, talking to endo and GP but they don’t know enough about resources :/

(EDIT: Does anyone have any idea why the mods of the PCOS group removed this post? Wtf? 🤔)

For those with insulin resistance pcos, struggling with getting regular period, ovulation, the entire absence of periods, weight gain, etc (I can’t speak on the other symptoms I have like hormone imbalance & high testosterone due to insulin resistance bc I haven’t gotten blood work again, but I assume it’s correct those issues as well given my natural period has came back already).

I am 2 1/2 weeks into taking compound tirzepatide (I go through Fifty410 Club Compound & Hallandale Pharmacy & select the option with NO additives, because I wanted the formulation to be the same as name brand Zepbound), & I just started a NATURAL period for the first time in 2-3 years! I have not had a natural period outside of an induced provera period for at least 2-3 years & it’s only been 2 weeks on tirz & it already is obviously fixing the insulin resistance powerfully enough to already induce a period.

In addition, I have lost an average of 10 pounds in these 2 1/2 weeks. Hopefully it’s not muscle or my butt being taken bc I haven’t been in the gym, but I plan on starting weight training asap!

I have tried many things, natural supplements, Ovasitol for a year, metformin etc & NOTHING really worked. The only thing Ovasitol did was knock my A1C down from 5.7% to 5.4% & it took a whole year of consistent use for it to do that, but it didn’t improve not one of my other symptoms.

No consultation fees, no monthly membership fees, all I did was pay $249 for an 8 week supply (might be 12 week supply because they gave me extra mgs that wasn’t expected for my second month, but if I don’t have to titrate up from 2.5 mg to 5 mg, this $249 supply will last me 3 months!

It is extremely affordable & worth it, & I recommend it to EVERYONE struggling with insulin resistance pcos!

This is NOT a paid ad, just a struggling young woman that has felt helpless regarding my disorder for years like I would never find effective solutions, that wants to help those in similar situations because I understand, & I wish I would’ve found & started tirzepatide years ago!

In this article, PBS explicitly says PMOS / PCOS is related to metabolic syndrome. What do you think?

Been on Tirz for my PCOS and obesity disease since November 2024. Have had success with losing some weight. I need to lose about another 15 to reach maintenance. BUT, I’ve been in a crazy stall since January. Nothing is budging the stall and YES I do all the thing like hydrate protein fiber macros weighted exercise sleep etc etc, yes still no weight loss. Also, I’m in perimenopause and on HRT. I’ve been adjusting those meds and checking labs to see what needs tweaking.

I have asked my provider if I can add on a stack with Metformin and she approved. I’ll be started 500mg a day first two weeks then to 1,000mg if I can tolerate any of the typical met side effects. I’m also adding in inositol (4,000mg).

Anyone have success with the combo of glp1 + metformin? +HRT ?

has anybody been put on semaglutide and not really lost weight & haven’t really had any symptoms improved?

i’ve been on wegovy for 2.5 months now - im only 10lbs down, and im still always exhausted, still having hairloss, i have more acne than before, etc.

i have an appointment today with my dr. i was thinking about bringing up triz instead. all opinions welcomed.

*i see a nutritionist, and fit all criteria to get it fully covered i.e. lifestyle changes for 6m, working out, different diets, etc.*

I got off Zepbound a little over a month ago to TTC.

The first couple of weeks were fine. I thought: yay! maybe I don’t need this medication and can save some coins… maybe my PCOS is reversed.

I know that’s delusional. I’m aware of the science. But I just felt so good!

THEN:

Week 2 I was expecting to ovulate… but was a few days late after a year of regular cycles. This of course made timing difficult and we ended up missing the best window.

By week 4, I felt awful. Full on monster luteal phase unsupported by Zepbound. I could FEEL that the medicine was washed out of my body. Crazy hunger. I felt like a blackhole bottomless pit. Craving sugar? Inflammed especially in my lower abdomen. Genuinely so bloated I could not breathe well.

And the cruelest of it all… I felt slight nausea. Which I now realize was hunger signals that my brain was not processing as hunger. Because the nausea would go away after I ate.

Anyway, I have now confirmed I’m not pregnant. I miss Zepbound so much and going to ask my doctor if I can stay on until I confirm pregnancy. It’s simply too hard to TTC with an irregular cycle.

I know everyone's body is different and everyone reacts the same, but my experience starting Zepbound has been so different from what I was expecting. And so different from what my friends and family experienced.

I did feel fuller longer and have less appetite for 3 days after my first dose. But since then I've felt completely normal. No extra fullness, no appetite suppression, no nausea, no GI issues. I even ate 5 donuts in a moment of weakness and felt fine after too.

I see my doctor in 10 days, it'll be after my 3rd shot and the day before my 4th dose. I know I'll have conversations with her about moving up to 5mg.

But I was hoping to stay on the 2.5 longer than a month. My doc said she has patients who can say on 2.5 for 3-6 months.

I'm worried I'm a slow responder, or that somehow my body is so broken that I won't respond at all.

Just looking for moral support to quiet that mean voice in my head.

For those with insulin resistance & PCOS that’s on tirz that ended up pregnant, I was curious if when you had to stop taking tirz when you got pregnant, if all ur symptoms & hormone irregularities came back while pregnant?

My concern is if tirz regulates my hormones & insulin resistance & thus slowing the excess facial hair growth, that getting pregnancy & having to stop tirz while pregnant can cause it to pick back up 👎🏽

I’m curious to anyone who’s on 5/2.5 maintenance dose/what your maintenance is on smaller amounts. How’s it going, do you use metaformin and berbine/ similar to help with food noise? What’s helped you maintain off Mounjaro or on small amounts?

Lastly, those that came off to try for/have a baby - how did you find it?

Had to get the PMOS in…

So question - how was everyone’s experience with ferritin, iron and b12 blood results?

I’m all ok all of them all the time. And I top up and feel better BUT I think my PCOS are worse.

So my question is for those out there, who like me track this.

What are your thoughts and experience?

Thanks in advance

I have PCOS & insulin resistance that has caused many symptoms for years ago. I also “possibly” have fatty liver due to an ultrasound from last semester. I started compound tirz 2 & a half weeks ago at 2.5 mg (took my 3rd shot 3 days ago). I was given 5 mg for my second month, but I just hopped on the scale & have lost about 8 pounds so far in this 2 & a half weeks. Im shocked because I thought with my level of insulin resistance & hormone imbalance, that it was going to take way longer to start working for me.

I’m happy about the weight loss, but that’s not my only goal. My main goal is putting my pcos in remission. I’m wondering if, since I have PCOS due to insulin resistance, if I should still go up to 5 mg dose to help better support my insulin resistance & hormone balance?

Also, I’m not sure where the weight was lost yet bc I personally don’t see a difference 😅 I hope it didn’t take from my butt.

Previously I was on Wegovy and then zepbound for a 2 years. Lost about 40-45 pounds and really loved it more because it helped with inflammation flareups with weight being an added bonus. Last year my insurance stopped covering it and I couldn’t afford it out of pocket at the time. Within the past 1.5 years, I’ve only gained about 5-10 pounds that fluctuates.

That being said, I’m starting to noticed I’m getting flareups and struggling with weight loss even with maintaining my GLP-1 exercise+diet changes.My theory it’s based on my inflammation coming back. Ideally I would like to lose another 20-25 pounds in the next year and thought this could aid in that again and lowering my flareups. So I’m thinking about paying out of pocket for the lower Wegovy dosages and just wanted thoughts on if anyone has done that? Alternatively, I’m open to the pill version as well.

Polycystic ovary syndrome (PCOS), a condition affecting more than 170 million people worldwide, has been officially renamed Polyendocrine Metabolic Ovarian Syndrome (PMOS) following a landmark global consensus study published today in The Lancet.

The new name recognizes that the condition is not a primarily gynecological disorder, but is instead a complex, multisystem condition involving endocrine, metabolic, reproductive, dermatological and psychological health. Additionally, the recategorizing will include updates to clinical guidelines, medical education and international disease classification systems, ensuring the new terminology is adopted consistently worldwide.

So hungry !!! Week 2 of 5mg

I was great the week 1 of 5 mg but idk why I’m so hungry on the second week. I walk every day for one hour and do weight lifting 2-3 times a week and Pilates twice a week.

Breakfast: veggies, sourdough bread and cottage cheese

Lunch: peanut butter and protein shake

Dinner: lamb bolognese pasta, or lamb hamburger, or chicken fajitas and with veggies (just depends on the day)

2L of water with electrolytes

As the title says, I’ve been struggling with a few cycles where the PMS is harsher than usual. it’s not something predictable as some months will go by with no symptoms but some months like right now I will get unusually low mood along with insane hunger at all hours. I was wondering if any of you also have the food noise down except that week before your period where you can eat the house down 😔 really makes u feel demotivated

I wanted to get some advice from everyone here. I’ve been struggling with weight gain and a very high appetite for the past 5 years. I never had this issue before, but suddenly things changed. My appetite increased a lot, I gained weight, and no matter how much I work out, I hardly see any results.

In 2021, I started taking berberine and used it for about a year. It worked well initially, but now I feel like I’ve reached a point where it’s no longer helping much.

I recently consulted a doctor who has been aware of my struggle for years, and he suggested trying a GLP injection. From what I understand, though, once you stop GLP treatment, there can be a chance of regaining the weight and having your appetite increase again. My biggest issue is my high appetite and difficulty losing weight, so I’m worried about relying on something that may only work short term. I’m looking for a long-term and sustainable solution.

Because of this, my doctor and I decided to first try Metformin 250 mg and slowly increase the dose over the next three months to see how it works for me. I feel Metformin may be a slower approach, but perhaps more sustainable in the long run since the dosage can be adjusted when needed.

I wanted to hear from others: how effective has Metformin been for weight loss, appetite control, and PCOD? I know GLPs are generally more effective, but I’m curious how Metformin compares. Also, for people who have used GLPs and then stopped them, what happened afterward? Did your weight come back or did your appetite increase again

Y'all I'm so happy. My doctor had to submit a PA for my Wegovy pill in an attempt to get it covered. Of course, Cigna denied it. My doctor submitted an appeal and I just got notice that it is now approved! I'm so happy. 🥹😭 I just wanted to tell people who would understand how wonderful this is. ❤️

hey! i had the stomach bug and my doctor recommended i skip my dose while sick, i am set to take my next dose tomorrow, i was curious if anyone has done this and if they experienced any effects from starting back on the same dose they were before. I am on 40 unjts of trizepitide for reference, thanks so much!