My GI is transitioning me to biologics as it’s clear that mesalamine is not strong enough for my level of inflammation. He has suggested either Entyvio, Skyrizi, or Tremfya and has given me some time to think about my choice before we reconvene to discuss later this week. He mentioned Entyvio has a very good safety profile as it’s “gut-specific” but after searching on this sub I see that means it could also take months before seeing any improvements on it.
For those who have tried any/all of these biologics, I’d love to hear about your experience. Did you ever reach remission, and if so, how long did it take? If it failed, how long did you give it before moving on to the next drug? Any weird side effects? I know it’s a very individual experience but feeling worried about ‘picking’ the wrong one and going back to square one.