u/Asleep-Author-876

I’m looking for some insight from people who have experience with B12 injections and folate/folinic acid.
I’ve been taking 1.5 mg B12 injections every other day for a while. For a long time I was only taking around 400 mcg folate with them, and I felt absolutely terrible — like a zombie. Nothing felt enjoyable, I had no emotions, no motivation, and I basically just lay on the couch waiting until I could sleep again. It felt like I had no dopamine or pleasure response at all.
At some point I started wondering if my folate dose was too low for the frequency of my injections. So I increased my folate to around 1.2 mg, and on the first day I felt almost euphoric, like I had found the missing link. But then after my next B12 injection, I went right back to feeling like a zombie.
After that, I increased my folinic acid to about 4.8–5 mg. That day I did notice a slight boost in energy, and over the following week I honestly felt like I was slowly improving and less zombie-like. However, I also started getting some pretty uncomfortable symptoms:
Strong pins-and-needles sensations in my legs
Burning pain/skin sensations
A weird dry/burning feeling in my mouth and tongue
Electric-like muscle twitches, especially in my legs
More anxiety and restlessness at times
Today I took another B12 injection along with some other supplements, and afterward I felt extremely depressed, restless in my head, sweaty, and intensely anxious. It was honestly scary. It has calmed down a bit after a few hours, but it really made me question what’s going on.
So my main question is:
Have any of you actually healed or improved better on higher doses of folinic acid/folate while doing frequent B12 injections?
Or do symptoms like burning, pins and needles, mouth/tongue sensations, twitching, anxiety, and mood crashes suggest that the dose may be too high or that something is out of balance?
I’m confused because part of me feels like the higher folinic acid helped me feel less like a zombie, but the new symptoms make me wonder if I’m overdoing it or triggering something else.

Hi, I have a question.

I am currently taking B12 injections: 1.5 mg twice per week. I also take 400 mcg of 5-MTHF daily. In addition, I am working on balancing several minerals based on HTMA results, because I feel like my whole body is out of balance.

Lately I started wondering whether my extreme fatigue could partly be related to taking a relatively low dose of folate while using a high dose of B12 injections. Because of that, I tried adding 5 mg of folinic acid daily for about two weeks. During that time I became increasingly anxious, nervous, and a bit paranoid in my head, as if it was too much for me. I stopped after two weeks.

After stopping, I gradually became more tired again each day. Today I tried 800 mcg of folinic acid. I do feel more anxious and mentally “wired” from it, but at the same time I also feel an immediate energy boost, slightly better mood, and less fatigue.

I also had extensive blood work done last week, including RBC folate, and I am waiting for the results.

My question is: I often read in B12 groups that people should take 5 mg of folate when using B12 injections, but I do not seem to tolerate that dose well. Is it necessary to slowly build up toward 5 mg to correct a possible deficiency, or could a lower dose, such as around 1.2 mg per day, be enough if that is what I tolerate better?

Hey everyone,

Are there people here dealing with hidden copper toxicity or copper toxicity shown on an HTMA? I’ve been working with a practitioner for about 12 days now, and honestly, I feel really awful.

If anyone else has gone through this, how long did it take before you started feeling better instead of worse?

My practitioner says it’s normal in the beginning and that it means the copper is starting to be released, but it’s pretty intense right now.

Would really appreciate hearing your experiences