u/BlakeCarConstruction

Hi all!

Onto month two of UC, and the 1 4g enema seems to have helped but not push my (mild) proctitis into remission, still having liquidy stools and some symptoms, so yesterday my GI increased me to 4g enema + x4 1.2g oral Mesalamine.

He said to call him if it doesn’t reduce my symptoms almost completely in a few weeks.

My question is:

Has anyone else had experience with high doses like this? Any problems short or long term?

If this doesn’t work, what is typically the next step(s)?

Do any of you get tattoos and have negative reactions? Doctor warned that 1-10% of UC patients have higher risk for pyoderma gangrenosum and a tattoo could trigger that. Thoughts?

Thanks all!

Hi all! Diagnosed with mild UC on 4/20/26 (cool date, huh?) got high as a kite!

Edit: 25M

Anyways I have a mild case and have been on mesalamine enemas since 4/20 and have had mixed results.

It is better, don’t get me wrong, but it certainly is not in remission. For my first month the Dr told me to eat like normal, don’t change my diet - which is hard because I can tell when I eat ‘bad’ stuff.

Anyone know why?

I have a checkup to schedule a 6 month colonoscopy and go over current symptoms next week, but I’m questioning how much my symptoms are supposed to go down?

I’ve gone down to 2-3 BM’s per day, but still have cramping, urges, and very soft/liquidy BMs (low/no blood)

Is this normal? Does it ever go all the way down?

I don’t have the results from the poop test yet.

Writing this from the toilet that I’m stuck on despite it being Mother’s Day I’m trying to be with family. This sucks.

What are the chances this gets worse and Mesalamine doesn’t work? Is this the expected level or should the medicine helping more than it is?

Thanks all, just scared and don’t know what outlook is.

John greens video on it helped me though.

Thanks all,

Your friend with UC