Just got Pathology Report, could use a hand reading it
Of course I'll talk with my doctor about it, but it JUST hit and I'd like to learn as much as I can before I meet with the doc.
I had a Partial Nephrectomy on May 9. Tumor was 5.5cm x 5 x 3.5. Patho result as follows:
A: Kidney, left, partial nephrectomy, left renal mass --- or 37:
RENAL CELL CARCINOMA, CLEAR CELL TYPE, WHO/ISUP GRADE 3. (SEE COMMENT AND CAP PROTOCOL)
Parenchymal resection margin, free of tumor.
B: Perinephric fat, left perinephric fat -- or 37:
Fibroadipose tissue, no tumor present.
Immunohistochemical stains show that neoplastic cells are immunoreactive for CD10, CAIX, Vimentin and immunonegative for CK7, Cathepsin K. BAP1 shows retained expression in tumor cells. These results support the above diagnosis.
TUMOR
Tumor Focality: Unifocal
Tumor Site: Upper pole
Tumor Size: Greatest Dimension (Centimeters): 5.4 cm
Additional Dimension (Centimeters): 5.3 cm
Additional Dimension (Centimeters): 3.5 cm
Histologic Type: Clear cell renal cell carcinoma
Histologic Grade (WHO / ISUP): G3, nucleoli conspicuous at 100x magnification
Tumor Extent: Limited to kidney
Histologic Features: Sarcomatoid or rhabdoid features not identified
Tumor Necrosis: Not identified
Lymphatic and / or Small Vessel Vascular Invasion (excluding renal vein and its segmental branches and inferior vena cava): Not identified
MARGINS
Margin Status: All margins negative for invasive carcinoma
REGIONAL LYMPH NODES
Regional Lymph Node Status: Not applicable (no regional lymph nodes submitted or found)
pTNM CLASSIFICATION (AJCC 8th Edition)
Reporting of pT, pN, and (when applicable) pM categories is based on information available to the pathologist at the time the report is issued. As per the AJCC (Chapter 1, 8th Ed.) it is the managing physician's responsibility to establish the final pathologic stage based upon all pertinent information, including but potentially not limited to this pathology report.
pT Category: pT1b
pN Category: pN not assigned (no nodes submitted or found)
ADDITIONAL FINDINGS
Additional Findings in Kidney: Interstitial chronic inflammation
Gross Description
A:
Kidney, left, partial nephrectomy, left renal mass --- or 37: A partial nephrectomy specimen (7.5 x 6.3 x 5.5 cm) with attached perinephric adipose tissue (9.8 x 6.3 x 2.7 cm). The specimen is oriented by the surgeon and there is a portion of renal sinus at the resection margin.
There is a 5.4 x 5.3 x 3.5 cm red–orange soft well-circumscribed tumor present. The tumor shows areas of hemorrhage. The tumor abuts the renal sinus and is 0.2 cm from the resection margin. The tumor does not grossly invade into the perinephric adipose tissue.
The remaining kidney parenchyma is unremarkable.
INK CODE:
Blue–resection margin
Orange–renal sinus
SECTION CODE:
A1–A3, tumor with entire renal sinus interface and closest parenchymal margin
A4–A7, tumor with perinephric fat
A8, nonneoplastic kidney
BM
B:
Perinephric fat, left perinephric fat -- or 37: Consists of multiple pieces of yellow adipose tissue (7.0 x 7.0 x 2.0 cm). The specimen is serially sectioned and no lymph nodes are grossly identified. Representative sections in cassettes B1–B3.
ML