Is anyone here involved in mathematical biology research? I am looking to learn more about this area. If you are involved in mathematical biology, I would appreciate any advice or discussion about current research problems.
Is anyone here involved in mathematical biology research? I am looking to learn more about this area. If you are involved in mathematical biology, I would appreciate any advice or discussion about current research problems.
Proton tunneling across hydrogen bonds in DNA has been proposed as a mechanism that can produce transient tautomeric states.
DNA however is constantly fluctuating: hydrogen bonds stretch and contract, bases vibrate, and surrounding water and ions rearrange. Since tunneling probability depends very strongly—often exponentially—on the barrier width and height, even relatively small structural fluctuations could potentially produce large changes in the instantaneous tunneling rate.
This raises a question whether proton tunneling in DNA should be viewed not as a fixed property of a particular base pair, but as a dynamically modulated quantum process, where the changing molecular environment determines when tunneling becomes more or less favorable.
Could rare conformations temporarily lower or narrow the effective proton-transfer barrier and therefore contribute disproportionately to the overall tunneling rate?
If so, perhaps the important quantity is not simply the tunneling rate at one equilibrium geometry but the distribution of tunneling rates across the fluctuating DNA environment.
Has this already been investigated quantitatively? Could molecular dynamics combined with quantum/open-system methods reveal something that fixed-geometry calculations miss?
I would be interested in perspectives from people working in this field
Hello everyone,
I am exploring research ideas related to origin of life and astrobiology particularly involving physical and mathematical modeling of prebiotic systems.
I am interested in areas such as:
Statistical physics ,Information theory ,Nonequilibrium systems ,Chemical dynamics ,Prebiotic chemistry, Mathematical models of early chemical systems
I would really appreciate hearing perspectives from researchers, or anyone with experience in these areas.I am mainly interested in knowing whether this seems like a reasonable and scientifically meaningful direction to explore, and whether there are important considerations I should be aware of before developing it further.
If anyone with experience in this area would be willing to share their perspective or have a brief discussion, I would really appreciate it.
Thank you
Hello everyone,
I am exploring research ideas related to origin of life and astrobiology particularly involving physical and mathematical modeling of prebiotic systems.
I am interested in areas such as:
Statistical physics ,Information theory ,Nonequilibrium systems ,Chemical dynamics ,Prebiotic chemistry, Mathematical models of early chemical systems
I would really appreciate hearing perspectives from researchers, or anyone with experience in these areas.I am mainly interested in knowing whether this seems like a reasonable and scientifically meaningful direction to explore, and whether there are important considerations I should be aware of before developing it further.
If anyone with experience in this area would be willing to share their perspective or have a brief discussion, I would really appreciate it.
Thank you
Hi ,I am a medical student with a strong interest in Quantum Biology. I have been studying research papers and reviews to better understand the field.
Some of the topics I have been reading about include proton tunneling in DNA and enzymes, electron transfer in proteins, radical pair mechanisms, and open quantum systems .I have found that discussing ideas with people who are actively involved in Quantum Biology would provide valuable perspective beyond what can be gained from reading papers alone. Along the way, I have also come across some research questions and ideas that I would ike to better understand from an expert's perspective.
If you think there are researchers ,research groups or laboratories that are open to discussing the field with students who are genuinely interested in Quantum Biology, I would be very grateful for any recommendations.
Thanks
Hi ,I am a medical student with a strong interest in Quantum Biology. I have been studying research papers and reviews to better understand the field.
Some of the topics I have been reading about include proton tunneling in DNA and enzymes, electron transfer in proteins, radical pair mechanisms, and open quantum systems .I have found that discussing ideas with people who are actively involved in Quantum Biology would provide valuable perspective beyond what can be gained from reading papers alone. Along the way, I have also come across some research questions and ideas that I would ike to better understand from an expert's perspective.
If you think there are researchers ,research groups or laboratories that are open to discussing the field with students who are genuinely interested in Quantum Biology, I would be very grateful for any recommendations.
Thanks
Hi ,I am a medical student with a strong interest in Quantum Biology. I have been studying research papers and reviews to better understand the field.
Some of the topics I have been reading about include proton tunneling in DNA and enzymes, electron transfer in proteins, radical pair mechanisms, and open quantum systems .I have found that discussing ideas with people who are actively involved in Quantum Biology would provide valuable perspective beyond what can be gained from reading papers alone. Along the way, I have also come across some research questions and ideas that I would ike to better understand from an expert's perspective.
If you think there are researchers ,research groups or laboratories that are open to discussing the field with students who are genuinely interested in Quantum Biology, I would be very grateful for any recommendations.
Thanks
Hi everyone,
I have a question about publishing in theoretical physics.
In fields such as quantum mechanics, general relativity, gravity, cosmology, astrophysics, and astronomy, can a research paper be published if it is based entirely on mathematical modeling and analytical derivations?
For example, if a paper introduces a new theoretical framework, derives equations, proves a theorem, or makes analytical predictions, is that sufficient for publication? Or do journals generally expect additional components such as:
1.Numerical simulations
2.Comparisons with observational or experimental data
I am aware that many influential theoretical papers were primarily mathematical, but I'm curious about current publication standards. How common are purely theoretical papers today, and what makes them strong enough to be accepted by reputable journals?
For those who have published or reviewed theoretical papers, what makes a purely theoretical paper strong enough to be accepted?
I'd appreciate any insights or experience Thanks