Will sperm making cells desensitize like leydig cells?
Do sperm-producing cells become desensitized over time like Leydig cells can from long-term suppression?
I know TRT/steroids suppress LH and FSH, lowering intratesticular testosterone and sperm production, but I’m asking whether the Sertoli/germ cells themselves become less responsive after suppression.
And if they do, does using hMG/FSH help maintain or restore fertility responsiveness better than hCG alone?