u/Effective-Guide-9115

How you can help save tirzepatide compounding in less than 5 minutes

​

First, if this is the 12th post about this, I apologize. My phone is broken and I'm having issues with it in general. I'm unable to effectively search the sub, but I want to get this information out as the clock is officially ticking.

​The FDA has opened the public comment period for Docket No. FDA-2018-N-3240. This is the one that matters. They are deciding right now whether to remove semaglutide and tirzepatide from the "503B Bulks List."

​If they remove them, the large-scale compounding pharmacies we all use will be forced to stop production.

​We all know the "Greed Factor" here. Big Pharma is pushing to end the "shortage" status so they can reclaim their monopoly and charge $1,000+ a month again. We cannot let them win by being silent.

​How to help in 2 minutes:

​Go to Regulations.gov and search for FDA-2018-N-3240.

​Click the blue “Comment” button. ​Tell them your "Clinical Need."

​Don't just say it's cheaper. The FDA cares about "Clinical Need."

Tell them: The brand-name pens don't allow for the custom, flexible dosing you need.

​The brand-name drugs are still functionally unavailable due to cost and local supply gaps.

​A drug that costs more than a mortgage is effectively in a permanent shortage for the average person.

The deadline is June 29, 2026. Please don't wait until June 28. If we don’t flood this docket with thousands of comments, they will assume we don’t care. They are required to read every comment made before they make a decision

I just wrote the 376th comment so there's not that many up there

​Link to the Docket:

Docket

​Let’s protect our health and our wallets. Go comment now!

reddit.com
u/Effective-Guide-9115 — 8 days ago
▲ 13 r/stakeus

I ran a year plus long experiment comparing Stake to other casinos. The results were not subtle. At all

I’m posting this knowing that it's likely going to be deleted but also because I’m tired of being told it’s all “just variance” or that players are imagining things when they say Stake drains balances faster than other platforms.

About 15 months ago, I decided to stop arguing in circles and actually test it. Between myself and four other players, we tracked gameplay across Stake and five other major casino sites using the same providers, similar bet sizes, and similar volatility levels. We documented deposits, session length, turnover, bonuses, wins, losses, and realized RTP over time.

After more than a year of tracking spins and thousands of dollars in deposits, I genuinely do not believe the difference is psychological. Stake consistently performed as an outlier in our tracking.

The biggest discrepancy was not even the wins or losses. It was the burn rate.

On most other sites, a $1,000 deposit usually resulted in a decent session. Almost always. Even during losing runs, there were enough small and medium hits to keep the balance moving and generate turnover before the bankroll finally died out. On Stake, that same amount disappeared *dramatically* faster on a consistent basis.

In many cases, we were seeing roughly 20 minutes of play on Stake compared to over an hour elsewhere using similar settings and games.

The turnover difference was even harder to ignore. On competing sites, a $1,000 deposit could often generate tens of thousands in wagering volume before reaching zero. On Stake, that same deposit regularly produced *far* less total turnover before the balance collapsed.

At a certain point, that becomes increasingly difficult to explain as simple variance alone.

For people who may not know, many slot providers such as Pragmatic and Hacksaw allow casinos to choose between different RTP configurations. Two casinos can technically offer the exact same slot while operating under very different payout settings behind the scenes.

I obviously cannot prove Stake’s internal configurations, but based on the data we tracked, the gameplay *consistently* behaved more like lower RTP versions compared to competitors using the same providers.

The Stake Originals made this even harder to ignore. Games like Plinko felt noticeably different compared to similar style games elsewhere. The data consistently showed long low return streaks and rapid balance depletion unless an extreme multiplier was hit. It created a gameplay pattern where balances bled downward with very little recovery momentum.

People often point to the weekly and monthly bonuses as proof that Stake gives back more than other platforms, but our tracking honestly suggested the opposite. If gameplay drains balances significantly faster, then a monthly bonus starts looking less like generosity and more like a partial refund on losses that happened much quicker than they should have.

When we looked at total cost to play, some sites with no monthly bonuses still ended up being cheaper overall simply because the gameplay itself lasted longer and produced more turnover per deposit.

I’m not claiming anyone was forced to gamble, I've never had a gun to my head and I fully understand the house always wins long term.

I’m well aware this will trigger the usual defensive responses from people who strongly support the platform. I’m not posting this to argue those points in comment threads. The data is the point, not the debate. But after spending over a year comparing platforms side by side, I no longer believe all casinos operate equally simply because they use the same providers or advertise similar RTP percentages.

Again, I noticed this discrepancy almost immediately when I started playing on social casinos, but every time I brought it up, the response was always the same: “It’s just variance.” So instead of arguing, I started documenting.

After more than a year of tracking deposits, session length, turnover, and realized RTP across multiple platforms, I personally find it very difficult to dismiss the differences as coincidence alone.

If other high volume players have been tracking similar data across different sites, I’d genuinely be interested in comparing results.

TLDR: The underlying data and session logs exist and were used in this comparison. I’m not going to argue by posting private records or respond to repeated requests for proof in comments. The post stands on its own based on the methodology described. I simply wanted other people to know and if you want to continue playing on there, that is your prerogative. I didn’t really understand the criticism around sweepstakes casinos before this. I do now!

reddit.com
u/Effective-Guide-9115 — 13 days ago

I imagine this will get deleted, and that's fine, but this is why I'm starting to question the legitimacy of this. My friend and I both have accounts on Crown Coins and we joined roughly around the same time, 3 days apart. We also have almost exactly the same VIP level give or take a few percentage points but they're both in the 20% range the on Silver tier... ​​​​so tell me why the races say something completely different for us? We are sitting side by side and at the exact same time they're different... if there's actually different races taking place, then they need to be transparent with that... but more than likely it's because it's a sham of some sort. In the nearly two years that I've been playing here, I've seen other people suggest that the races weren't fair and that they were dropped down many levels (2nd place to suddenly 30th or something for example) at the very last minute but I just brushed It off as slots are volatile. But now after seeing this, ​​​​​I'm almost willing to bet that half of these people don't even exist and the lack of transparency is super troubling ​​​​​​​​​​​​​​. I think I'm done defending the integrity of social casinos. This isn't the first clue that things aren't on the up and up with them, this is really just kind of the icing on the cake ​​for me. Look at the time stamps and everything this is my friend's screen and my screen ​

u/Effective-Guide-9115 — 18 days ago