u/Eiszie

Should I go back to 150mg XL after 7 weeks on 300mg?

I was on 150mg XL and it actually did wonders for me, I was motivated and happy, but it just didn't fully help me during my PMDD week. I know wellbutrin isn't necessarily a solution for PMDD (I was actually taking it for MDD), but the 150mg did help a bit tho. I had been scared of birth control so I decided to try 300mg xl first before birth control. My experience on 300mg has basically had not many positives. For better or for worse, I don't care about anything. I'm super demotivated, apathetic, anhedonic, numb, and no appetite. I've been on it for 7 weeks now and wonder if I should bother 1 more week or even longer. The apathy has been getting to me for a while and it's just getting to me more. I'm thankfully not really depressed, but I just don't feel anything. I haven't felt good at all in over 2 months. Things that usually interest me don't really interest me at all. I'm thinking of going back down to 150mg and then trying to add birth control. For those who went back down to 150mg, how long did it take for you to feel better?

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u/Eiszie — 1 day ago

I was on 150mg XL for 3.5 months and after 6-8 weeks it had finally kicked in and was great, except for during the week before my period, to which I also have PMDD. I know Wellbutrin isn't necessarily one of the main prescriptions to treat PMDD, but I was prescribed it for my MDD, which it worked great for and a little bit for PMDD. Before Wellbutrin my PMDD week would be a 1/10 in terms of mental health, and after I think it ranges from 3/10-6/10, which is still an improvement, but not enough. So my doc and I decided to try upping to 300mg first before trying something else.

I've been on 300mg xl for 4 weeks now and the first 2 or so weeks were absolutely brutal. Nausea, dizziness, sensitive stomach, no appetite, light sensitivity, mood swings, irritability/anger, demotivation/anhedonia, and shaky hands. At 4 weeks, some of the side effects have gone away except for absolutely no appetite, sensitive stomach, and demotivation/anhedonia/emotional blunting. I ironically just don't care about anything at all. Nothing excites me. I also kind of can't feel my feelings. I also think I've been having some memory issues. I'm thinking of trying to stick it out a little longer since it took 6-8 weeks for the 150xl to work for me, but I can't lie that I'm scared and discouraged.

What if I go back to 150xl and it no longer works for me? Anybody who increased to 300mg xl, how long did it take to work for you? If you had anhedonia as a side effect, did it go away? I know Wellbutrin is used for appetite suppression, but I really hope my appetite comes back.

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u/Eiszie — 20 days ago