u/Equivalent-Estate-74

Nov 23 - 5.2cm mass left kidney
Feb 24 - radical nephrectomy, left kidney & 6 lymph nodes
Mar 24 - grade 4 ccrcc, microscopic cancer cells in 2/6 nodes
Apr 24 - commenced Pembro
Jun 24 - Pembro not working, return & spread & no longer curable
Jul 24 - Tivozanib- not as effective as hoped, so in
Sep 24 - Lenvatinib & Everolimus began
Dec 24 - scan results = shrinkage then 18 months stable
Apr 26 - progression & spread to liver, spine x2, lungs, psoas muscle
May 26 - started Cabozantinib

51 yo female

Just some questions really -

Has anyone had similar where immuno didn’t work for you? What were your next steps?

Those on Cabo, what side effects did you get & how soon did they show up?

Any positive stories at this stage?

Thank you!