u/Firm-Oil6308

Lovely community, I need your helpful comments here, o recently submitted a manuscript and it has DIA acquisition with two study groups each had n=4 biological replicates. I reported volcano with P<0.05 and curated the text as “nominally significant” because If I report FDR in volcano, nothing or maybe 1 or 2 IDS stayed significant when my data had almost 5K proteins. Reviewers got back saying repeat FDR in volcanos instead and I don’t know how to justify it. Please advice