u/FrameElegant326

▲ 3 r/mito

Future Children - Melas

Hello all,
My wife and I are looking to have children , she is 33 and I am 33.

My wife underwent some pain growing up, being premature for starters and requiring open heart surgery at 21. However since then she is healthy, only issue was hearing loss. Her sister, perfectly fine had a child before us and noticed her child was having lactic acid episode which prompted her to go to a doctor. This doctor came back saying her son had 80% melas Hetroplasmy which prompted the whole family to get tested. Her sister came back 75% my wife came back 54% and their mother never tested but is still alive and seems to be well.

Since then her sister’s son is doing okay, aside from short stature he doesn’t seem to have any severe issues and her sister is having another child - a girl.

This leads me to wonder, with my wife I worry if I should attempt natural pregnancy, or possible ivf with testing to find the least infected embryo if this even helps. What is also interesting is we made contact with a NYC Colombia based doctor who specializes in melas and I am hopeful to hear him out but my wife seems to think there is no hope and we either do those two options above or egg donor which isn’t on my top list to do.

Has anyone ever experienced this? Am I dumb to have hope that I will have a healthy child? Does her Hetroplasmy being less than her sister help us? Bit stuck what to do here but again would love feedback if anyone else experienced this.

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u/FrameElegant326 — 6 days ago