u/GeneralAltruistic506

Starting HRT with anxiety and depression

I’m 52, in late perimenopause. My depression and anxiety have been well controlled with Wellbutrin and Prozac for more than 15 years - until the last year. Had thyroid and ferritin checked and then wondered if advancing perimenopause was a factor. Also have fatigue even with good sleep, multiple wake-ups, lack of motivation/anhedonia, overwhelm, and dry EVERYTHING. No flushes or sweats, however.

I’ve just received a prescription for .25mg Divigel and 100mg progesterone (which seems like a standard beginner dose) I am afraid of the natural side effects some people experience when adjusting to HRT. I am starting a new job next week and not being able to control (or at least mask) my mindset would not be good.

For any of you who struggled with mainly mood symptoms pre-HRT, what was your experience with the first month or dose adjustments? Were the mood effects you experienced comparable with your baseline? Were you able to function at work? I know I will be hyper vigilant either way, but I love to hear your experiences.

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u/GeneralAltruistic506 — 29 days ago