Roast my setup, I'm too busy reading to notice!
Lots of setups; I wanted to join the club and post mine.
I'm using Project Title plugin with a few patches (listed in the last image). I was also able to get solitaire and minesweeper plugins running on this, mostly I was just to see that it was possible. The home screen is organized into 4x3 folders with authors, topics, or other genres. The books are 3x3 in each folder; all rounded covers with some slight changes made to the status icons. The status bar is set to overlap and display chapter name, completion %, page count, and pages left in chapter. OpenDyslexic font size 13, margins are tiny, I like to use the full page! It took a while to finally dial in all my defaults and make it all perfect. There is no significance to the page I used for the screenshot; it's just the page I was on when I figured out how to make a screenshot (diagonal swipe from any top corner to the opposite bottom corner).
I had this exact setup on my Clara Color and I recently made the switch to the Clara BW. The color screen was beautiful, but for the amount of reading I do it wasn't working for me. The screen on the BW is bright and clear; no graininess from all the extra pigment.