Tl;dr Does anybody take or has anybody switched to gastric resistant (enteric coated) prednisolone years after their transplant (kidney) ?
Hi everyone, sorry in advance for the essay, any advice would be hugely appreciated.
I had my kidney transplant 10 years ago. I've been on 5mg uncoated prednisolone for the whole 10 years. I also take tacrolimus.
Last year I had PTLD (lymphoma due to being immunosuppressed). Thankfully I'm in remission but the chemotherapy involved taking high dose pred (100mg a day) which subsequently destroyed my stomach.
I have been in agony every day for the last 15 months, endoscopies showed gastritis.
I eat a perfect anti acid diet. I took high dose PPIs for 14 months with no benefits and horrendous side effects, and H2 blockers don't seem to do anything.
I therefore believe the continual irritation from the daily 5mg of uncoated pred is preventing my stomach from healing.
As a last resort I'm thinking of asking my transplant team if I can transition over to gastric resistant prednisolone, but ideally I don't want organ rejection or adrenal insufficiency!
I figured I could transition over slowly using the 1mg tablets, maybe 1mg per month or something.
I can't find any information about switching so long after tx and would love to hear anybody's experiences before I bring it up with them.
So has anyone here switched over to gastric resistant pred after being on uncoated pred a long time after transplant?
Or is anybody on gastric resistant pred?
Thanks and all the best to you all!