u/Imaginary-Train-2728

My mum has had 1st line treatment, surgery, 2nd line treatment, 3rd line treatment. But, the tumour still came back and spread to the liver. There are no trials in the UK for her to join.

She does have some money from when my father passed away and we're wondering what a realistic timeline would be if we were to go the USA and get Daraxonrasib through the expanded access program?

I understand the steps would be

- Registering with an oncologist

- Sending a referral to Revolution Meds

- FDA review

- IRB review

- Drugs shipped

She currently has a prognosis of about 3 months. So, it would only really be worth it if she's about to access the drug in the next 4 weeks. She's about an ECOG 1 at the moment.

mum was diagnosed with pancreatic cancer in april 2025 - she had a 6 cycle round of chemo (folfirinox) - this didn't shrink the tumor but did shrink some of the lymph nodes and allowed her to have the whipples surgery (august 2025).

she had another 6 cycle round of chemo (GemCap) about 2 months after surgery (october to december 2025).

found out in jan that there was regrowth of the tumour at the surgery site and it's spread to the liver.

she had 4 cycles of irinotecan based chemo, had a scan a couple weeks ago and there was still growth in the liver and pancreas. her oncologist said clinically it's had no effect on stopping or slowing the growth so didn't recommend finish the the full cycle. - she's now stopped chemo.

in Jan when we found out, the doctor said, without chemo it would be a prognosis of 6 months. this chemo she's just had has had no effect, basically the same as not having had chemo at all. so, she has a three month prognosis.

they've given a lot of different medications, at the moment tablet steroids are really helping her a lot - but i'm wondering realistically what is it going to be like now. she has a lot she wanted to do, trips, holidays and

i think her and my siblings have in their minds things will start to get bad around that three month mark but i'm just so worried about what the deterioration is going to look like.

it's only been 2 weeks since she's ended chemo so, what happens now. what is it going to look like. and i know it is different for every person, but, i just want to be prepared for any outcome