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The World Health Organization (WHO) has updated its tracking of the rare Andes hantavirus outbreak, with total confirmed cases growing from 11 to 12. While the WHO assesses the global public health risk as low, the risk remains moderate for exposed passengers and crew. The outbreak has resulted in 3 deaths, highlighting the severe 30% to 50% mortality rate historically tied to this strain. The Andes variant is uniquely dangerous as the only hantavirus capable of limited human-to-human transmission through close, prolonged contact.