Borderline MMA and Homocysteine After First Injection
My only B12 intake has been one or two multivitamin pills daily with 2.5 mcg of cyanocobalamin per pill. Serum B12 has always come back normal or high (676, 735, 947 across different labs), and every doctor used those numbers to rule out B12 deficiency. I decided to test MMA and homocysteine this week.
Three days before this draw I injected a B-complex ampoule (100mg B1, 100mg B6, 1mg cyanocobalamin) for the first time. Dumb, I know. So everything below is suppressed. Results:
- MMA (whole blood): 0.38 nmol/mL (normal ≤0.40)
- Homocysteine: 11.9 µmol/L (normal <12.0)
- Holotranscobalamin: 43 pmol/L (normal 21 - 123)
- Serum folate: 7.45 ng/mL (normal 3.89 - 26.80 but the FAQ says >15)
Non-smoker, no alcohol or drugs. Chronic fatigue, long sleep requirement with heavy sleep inertia, attention problems. I've seen multiple specialists across several countries and conducted extensive blood tests, but no dice. Any thoughts?