UPDATE: Oral Microbiome Transplant
*FAQS*
This is an update on the oral microbiome transplant at University of Washington in Seattle.
Please see my previous post for context and details about the trial here, as I won’t be answering questions about that - https://www.reddit.com/r/badbreath/s/cQ5nQHs1V8
I visited recently and took part in the trial. As I could not find a suitable donor, the scientists found one for me.
I mentioned that others want to take part but don’t have donors, and the scientists have said they can see if the dental students at the university could become donors.
They also published an article about it recently, if you want to take part you can contact them using the details in the article. *for some reason the link was removed so I’ll paste it again in the comments
*MY RESULTS*
For context, I have room filling (nasal & oral bb) and have had this for over 10 years. I have had various surgeries and tried all the different probiotics and mouthwashes etc. The only things that have been successful for me were metronidazole, but the bb returned after finishing the course, and the sodium hypochlorite rinse which gives me up to 8 hours bb free as long as I don’t eat.
I travelled to Seattle from the UK, the transplant took a few hours. I used my sodium hypochlorite rinse several hours before, to nuke my existing bacteria, and thoroughly neutralised this with water for hours before the transplant to ensure it did not kill the new bacteria - they performed a full dental cleaning, including cleaning of all soft tissue (& back of tongue) with glycine powder to dislodge any biofilm. Then I rinsed and gargled with the donor solution and they syringed (blunt needle) some into the gaps between my teeth.
The transplant initially completely removed my bb. I was able to get a 10 hour flight with no issues, despite eating and not brushing my teeth. I was totally bb free for 3 days post transplant, something which has NEVER happened before.
Unfortunately, the bb gradually started to return after day 4 - I guess my own bacteria managed to take over again. This was really devastating and destabilising for me, as I believed I had been “cured”. However, I still think this is a breakthrough as it shows that the transplant works and for some people it could be permanent.
*OTHER’S RESULTS*
A few others have also participated, and did not report an improvement. However; they did not use the rinse I used and the team also did not observe any bb from any of them when they visited so their level of odour is unclear.
I would only recommend trying this if you have exhausted all other options - dental, ent, gastro, antibiotics, surgery etc.