Wellbutrin, Zoloft, and lamictal
Before I started Wellbutrin I did a lot of research and there wasn’t much here to help so I’m hoping this may help the others following the same path.
To start I am a diagnosed epileptic
Factors that were in play that made my doctor comfortable putting me on Wellbutrin
- I haven’t had a seizure in 6 years
- The seizure I had 6 years ago was caused by my choice to abruptly stop taking my lamictal/ I was pregnant with my daughter.
- I am on lamictal and my seizures respond well to it. I haven’t had one since I started taking it (minus the one I mentioned before)
Second part
The drug breakdown
- I’ve been on lamictal 100mg 2x a day for almost 10 years
- I was put on Zoloft 100mg in October (7 months ago)
- I took my first Wellbutrin 150mg xr yesterday 5/13/26
Ok so side effects
Lamictal - 0 side effects nor did i really notice a difference, just that the seizures stopped.
Zoloft - I started at 25mg and slowly made my way up ( I took notes every day since starting 25mg if anything’s interested I’ll share) but definitely increased anxiety, sweating, dizzy, restlessness, then super tired. None of this lasted long.
Wellbutrin - like I said earlier I’m only on day 2
5/13 first day felt fine became irritable in the evening very tired with headache by 8pm slept great
5/14 took this morning at 10am again. Just feel normal a little jittery and again irritated.
Most importantly is only been 2 days yes, but no seizure activity yet.
Reason for each drug
Lamictal - anticonvulsant
Zoloft - anxiety
Wellbutrin - energy and sex drive that Zoloft took away.
I used brand names in this just because they’re easier but I take the generics of all
Lamotrigine
Sertraline
Bupropion