u/Original-Hamster3572

I've been trying to figure out why I have consistently high TSAT and low TIBC, and I came across information on hemochromatosis. Can you help me interpret my labs?

I'm 29F and have been menstruating since 14. My most recent labs, which I don't think I fasted for, are:

• Iron: 107 mcg/dL
• TIBC: 191 mcg/dL (reference: 262–502 mcg/dL)
• TSAT: 56% (reference: 20–40%)
• Ferritin: 119 ng/mL – though the lab report said ferritin levels can be falsely decreased by biotin supplements, and I was taking a vitamin B complex tablet with 1000% DV of biotin at the time

These levels have been relatively consistent over the past several years:

https://preview.redd.it/g10qia02tljh1.png?width=2176&format=png&auto=webp&s=29a15785197af2272ec7116eb35448421f2541b9

I have a lot of health conditions (ulcerative colitis being the most relevant one for iron) so it's hard to tell whether I have symptoms related to my iron levels. My health conditions and low weight also make me ineligible to donate blood.

Based on my Ancestry results, I don't have the C282Y mutation but I'm heterozygous for H63D.

My questions are:

• Does it seem like I might have some form of hemochromatosis? If not, any other ideas about my low TIBC and high TSAT?
• Is it possible to have both hemochromatosis and a non-iron-deficiency form of anemia? I'm wondering especially about anemia of chronic disease / anemia of inflammation (ACD/AI).
• Should I be avoiding iron supplements? My doctors are always recommending these because I have borderline low hemoglobin and blood loss from menstruation and ulcerative colitis.

Thanks in advance!