When to anticoagulate for ESUS?
It was my understanding that the trials examining ESUS demonstrated no benefit of DOAC over antiplatelet. Yet there are a few attendings I work with who will still anticoagulate if the stroke pattern appears to be very clearly embolic and/or if there are underlying conditions that may increase thrombotic risk like underlying malignancy. Some will even do very extensive work up for thrombosis such as genetic hypercoag work up in a 70 year old or 4 extremity Doppler even in the absence of DVT signs/symptoms.
I’m genuinely just curious because I get some opposing messages and when the attending switches then the new attending on service may cancel the work up the prior attending said to order. So just confused and hoping for some clarity.
I know some of this may just be different practice preferences so if that’s what it is then I’m happy to accept that. I just wanted to make sure there wasn’t some important piece of information I was overlooking.