Help :( POI, Progesterone Intolerant, and Hypertonic Pelvic Floor Syndrome
I’m 28 years old, I was diagnosed with Primary Ovarian Insufficiency at 26 following a car accident where I broke my spine, pelvis and sacrum - my body stopped creating hormones, eggs were damaged and I can’t have children easily, etc to where I now need HRT to protect bone density.
My problem, I don’t tolerate progesterone at all. It’s been a year and a half of trial and error with different timings (cyclical vs continual), different dosages (100mg - 200mg), and I still feel absolutely awful. Normally just deal with the insane bloating that adds 10 pounds, but this most recent cycle has landed me in the worst depressive episode I’ve experienced and it’s all tracking with progesterone.
My other problem however, from a result of the car accident, I have hypertonic pelvic floor syndrome (my pelvic muscles don’t relax - excruciating painful and exhausting), so vaginal progesterone goes out the window.
I’m nervous about the efficiency of progesterone cream, and so exhausted that I don’t want to try other progestins. The IUD also makes no sense to me as my body clearly does not like any form of progesterone (I did trial the vaginal).
I’ve been looking into Duavee and am interested, but feel like my doctor isn’t going to advocate because my body is actually producing no progesterone.
My overall dilemma: I am not producing progesterone naturally, but I’m also severely intolerant. I don’t want to be on it at all, but understand its purpose. I don’t know what to do.
I feel like giving up, it’s been years of suffering and I’m just exhausted.