So I listened to a retro game podcast about the TI-99 and heard about this game Alpiner (1982). I searched for it, saw the video thumbnail, chuckled and thought I should share it.
If a dev is here, please tell us if this was somehow part of your childhood and maybe a subliminal inspiration ;)
TL;DR:
I took 600mg to 900mg of Thiamine (B1), 1ml of Cyanocobalamin injections (stupid) and 1.2 mcg Methylfolate. All daily.
After the B1 (before B12) my extreme muscle pain and chronic fatigue vanished for 3 days then slowly returned so that I'm not really able to walk at the moment.
I will try Hydroxocobalamin injections and sublingual Methylcobalamin in the next few days but I'm wondering what the role of the Thiamine is and what I should keep in mind.
Labs somewhere below.
My background:
IDB (Ulcerative Colitis) with chronic fatigue for years. This year I started to develop crazy muscle weakness and pain after mild activities, which got stronger and stronger whereas before the fatigue was a more general kind of weakness and brain fog (I've done some dry fasting, maybe the was the catalyst).
So at some point I couldn't make myself something to eat anymore as my arms were destroyed as well. Then I stumbled over [this study](https://www.sciencedirect.com/science/article/pii/S2772572324001274?utm\_source=chatgpt.com), where they gave IBD patients high amounts of Vitamin B1. That led me to the B12 rabbit hole and I decided to get B1 and B12 and test it together.
Now this is where my actions become a bit stupid. I was about to do some labs anyway . But my Gastroenterologist would only take my B12 Serum, so I tried to ask the lab itself to take the other markers as well, but they wouldn't do it after the initial order.
Point is, now I only have the B12 Serum. I was suffering for weeks already and my other more reliable doctor was on vacation and I wanted to do anything to make my situation better.
So I said fuck it and started 600mg B1 on midday and in the evening 1ml B12.
Of course I also was stupid or fatigued enough (or both) to order the wrong B12 (Cyanocobalamin). Noticed that after my 2nd injection.
SonI fucked that up.
Anyway, a couple of hours after taking the B1 the pain just vanished. I couldn't believe it. I thought that's it. It's not me/cfs, maybe I have a genetic B1 deficiency.
The day after the first B12 I also had some extreme sensations related to my perception and cognitive capabilities. The world appeared much snappier, I could follow conversations much better and so on.
Now it's day 5, I've taken four B12 shots of Cyanocobalamin (did it daily as I thought I might as well use it until the Hydroxocobalamin arrives) and ended on 900mg of B1.
I also took 400, then 800, then 1200 mcg of Methylfolate without any research at all (stupid).
On day 4 to day 5 the pain in my legs and the fatigue returned.
I cancelled the Methylfolate for now, just in case, though it's hard for me to imagine it would have had such an impact.
I also got the results of the test:
B12 labs: 1448 ng/l (197-771)
Folate: 8.1 mcg/l (> 4.0)
Ferritin: 60 mcg/l (30-400)
So I guess that could mean my B12 doesn't get into the cells? My next step would be to try Hydroxocobalamin injections and Methylcobalamin sublingual at the same time.
My question is: what could be the role of B1 here and how should I proceed with it?
But any suggestions are welcome regarding my next general steps.
Btw:I took magnesiumglycinate, D3 and drank coconut water daily.
I Remember this only from my childhood, so I got very sparse information.
It should be pre 2005. Don't know the artist, but it has this sort of "washed out" look that I normally don't like. Visually it's like the contrary to Don Rosa, at least to me. But storytelling wise it's a pretty grounded adventure story/Barks-like approach.
They get lost in the desert (I think their vehicle broke down), almost die of thirst and are rescued by blind underground people who give them shelter. I don't remember what further happens in this part of the story.
However there's a panel that haunts me to this day and which is the main reason I'm looking for it. In the end the 'Ducks' decide to leave the underground people and head back to civilization. They get some provisions but barely make it back. One of the final panels shows them greedily drinking water from giant beer glasses. To this day the thought of the panel makes me physically feel the thirst and the feeling of finally getting liquids so it's my most vivid memory :D
Thanks for any help
SOLVED! Thanks to u/Much-Jackfruit2559
original title: "Zio Paperone e "l'oro" del Calderon del Diablo" German title: "Gefangen im Teufelskessel"