
BioVie Phase 2 Trial on Bezisterim for Long COVID fails
bezisterim is an oral drug that crosses the blood-brain barrier and is believed to reduce inflammation and improve insulin sensitivity, in Long COVID.
Unfortunately it doesn't work. ☹

bezisterim is an oral drug that crosses the blood-brain barrier and is believed to reduce inflammation and improve insulin sensitivity, in Long COVID.
Unfortunately it doesn't work. ☹
• Filed in state court in St. Lucie County under Florida’s consumer-protection law (FDUTPA), not as a personal-injury case.
• The state says Pfizer told people the shot was safe and that it had not seen “a single safety signal,” while allegedly knowing of risks it did not fully disclose — including myocarditis and pericarditis in minors, and concerns about pregnancy, including miscarriage.
• It also says Pfizer urged vaccination to protect others and stop spread, even though the company had not tested whether the vaccine stopped transmission.
• Pfizer is accused of spending more than $10 billion on advertising from 2020 to 2023 and making more than $80 billion from vaccine sales, then raising the price from about $30 a dose to roughly $110–$130 in 2023.
• The complaint cites Bourla’s compensation of nearly $102 million over that period and a comment calling people who raised safety concerns “criminals.”
• Florida wants an injunction, civil penalties of $10,000 per violation ($15,000 if seniors or disabled people were affected), and return of profits.
Reuters news article on this - https://www.reuters.com/business/healthcare-pharmaceuticals/florida-attorney-general-sues-pfizer-ceo-over-covid-19-vaccine-claims-2026-10-01/
Rozanolixizumab is a monoclonal antibody that targets the neonatal Fc receptor (FcRn). This receptor normally protects antibodies from breakdown, so blocking it leads to a reduction in antibodies.
The drug is already approved as a treatment for myasthenia gravis.
🔬 Key Takeaways:
✅ The Genetic Blueprint: How hereditary fibrinogen amyloidosis (2007) first proved that fibrinogen proteins could misfold into sticky, abnormal structures.
✅ The Disease Expansion (2010–2019): How researchers systematically uncovered the exact same microclot structures in Alzheimer’s, type 2 diabetes, stroke, rheumatoid arthritis, lupus, and severe migraines.
✅ The Tech Breakthrough (2016): How switching from electron microscopy to Thioflavin T fluorescent staining allowed scientists to measure microclot size and quantity directly in blood samples.
✅ The Pandemic Shift (2020–2022): How microclotting was confirmed in COVID-19, Long COVID, post-vaccination states, and Chronic Fatigue Syndrome (ME/CFS).
Obvious scientific fraud and the authors involved don't do much to correct their work.
(*This youtuber actually isn't a fan of the medical freedom movement and people who don't trust medical authorities.)
Book Review by Robert W. Malone, MD, MS
On July 29, 2026, Anthony Stephen Fauci sat down at a witness table under subpoena. He invoked his Fifth Amendment right against self-incrimination one hundred eleven times.
A man who spent forty years explaining himself to the American public, in more television appearances than anyone can count, declined to explain himself under oath. Days earlier, Senator Rand Paul had released 1,141 pages of Fauci’s private diary to the world. Something in those pages made silence the better option.
Peter Navarro has read all 1,141 pages. He has also read the earlier volume, the one Fauci emailed to himself from a government server on July 11, 2015, covering the anthrax letters, the smallpox scare, the bird-flu wars, and Ebola. Why Fauci MUST Rot in Prison is what he found.
I should tell you at the outset that I am not a neutral reader of this book. Navarro asked me to review the manuscript before publication, specifically the sections concerning me and the sections concerning Dr. Vladimir “Zev” Zelenko. I went at those sections the way I would go at a paper I had been asked to referee. I will come back to what happened when I did.
The book rests on a simple premise. Anthony Fauci wrote down what he actually thought. Then he went on television and said something else.
He defends his decision to reject Moderna's mRNA flu vaccine application, which the agency has since approved following his departure, and explains a controversial internal memo in which he wrote that "at least 10 children have died after and because of receiving COVID-19 vaccination" and that "for the first time, the US FDA will acknowledge that COVID-19 vaccines have killed American children." The official FDA report made public after Prasad left identified zero "certain" childhood deaths linked to the vaccine, with five classified as "possibly" and two as "probably."
"They changed the report. I had a draft report with 10 [likely deaths]. They changed it after the media publicity of my letter," says Prasad, who believes the data were altered for "political or professional" reasons.
While he entered the job with the intention to raise the standards for drug approvals, Prasad says his firsthand experience witnessing just how entrenched the political and bureaucratic problems at the FDA are has made him "a bit more libertarian" and open to the idea of "Consumer Reports–style agencies" competing with the government on drug approvals, which would offer "people in America greater flexibility in what kind of products they can try."
Prasad also reacts to the recent publication of top COVID adviser Anthony Fauci's diaries, whom he says is likely guilty of criminal conduct for his role in funding gain-of-function research.
"I can't think of a single policy [Fauci] actually got right when he was running the federal health policy," says Prasad.
Malone also talks about the acip committee not presenting its work on recognizing vax injury:
I served as vice-chair of ACIP and as a member of its COVID-19 vaccine workgroup under Retsef Levi. Contrary to claims that the committee did nothing for the vaccine injured, an enormous amount of work had already been done. Many people contributed thousands of hours reviewing the evidence, debating definitions, developing recommendations, and building a framework for federal recognition of chronic COVID-19 vaccine injury. By February 15, 2026, that work had produced a completed report. What we were not allowed to do was present it.
Aaron siri talks about the revolving door between the fda and the pharma industry.
A woman in her 40s became the first reported fatal case of transdermal ivermectin toxicity after applying large amounts of ivermectin to damaged skin for a month. What started as treatment for scabies ended in a tragic outcome that highlights the dangers of medication misuse.
Ivermectin is a highly effective antiparasitic medication when used appropriately, but like any drug, safety depends on dose, route of administration, and proper medical supervision.
In this video we examine a newly published medical case describing what appears to be the first documented fatal poisoning caused primarily by ivermectin absorbed through the skin.
🔬Topics covered:
• What ivermectin is and how it normally works
• The patient's scabies diagnosis and treatment history
• Early warning signs that appeared before the medical emergency
• The growing interest in ivermectin as a potential cancer treatment and why current human evidence remains insufficient
A newly unclassified CIA summary released by Sen. Rand Paul shows that on May 7, 2020, Pfizer board member and former FDA commissioner Scott Gottlieb told the CIA that national COVID seroprevalence was about 20–25%, far higher than what he was saying in public.
This paper argues that sudden death wasn't coded correctly for the pfizer clinical trial. If they had done that, there would have been 10 sudden deaths in the control group for Pfizer/BioNTech BNT162b2 mRNA vaccine and 5 in the placebo group, which is a 2-fold increase.
Objective: To characterize the Sudden Unexpected Death (SUD) signal in the Pfizer/BioNTech BNT162b2 mRNA vaccine clinical trial (C4591001) and evaluate factors that may have obscured its detection.
Methods: We conducted a forensic analysis of the original trial documents released by Public Health and Medical Professionals for Transparency (PHMPT.org). All-cause mortality within the first 6 months was reviewed, with SUD defined as death occurring suddenly and unexpectedly in an apparently stable individual.
Results: Of 38 all-cause deaths reported in the 6-Month Interim Report, 15 met criteria for SUD (39.5%): 10 in the BNT162b2 arm (6 males, 4 females) and 5 in the placebo arm (3 males, 2 females). This represents a 2-fold increase in SUD incidence in the vaccinated group compared to placebo. Autopsy data were unavailable for all cases; only 4 of the 15 SUD deaths underwent autopsy, with original reports not provided. The reported cause of death for 8 SUD cases was "cardiac arrest" or "cardiopulmonary arrest," which does not elucidate the underlying etiology. One death was attributed to "sudden cardiac death" and another to "aortic rupture," suggesting autopsy findings were summarized but not detailed in the Case Report Forms. Age-stratified analysis indicated a shift toward younger age at death among vaccinated males with SUD (median 52.5 years vs. 65.5 years in placebo, p=0.04). No temporal association was observed between vaccine administration and SUD occurrence when comparing intervals from dose 1 or dose 2 to death.
Conclusions: The SUD signal in the BNT162b2 trial was obscured by three methodological factors: (1) exclusion of sudden death from the predefined Adverse Events of Special Interest (AESI) list, (2) inconsistent reporting of dates of death, and (3) absence of standardized autopsy data. These limitations impeded comprehensive safety signal detection. Future trials of novel vaccine platforms should include sudden death as a predefined AESI and mandate autopsy for unexpected deaths to enable accurate causality assessment.
Author Simon Makin interviewed leading researchers on the leading hypotheses of Long COVID, including SARS-CoV-2 persistence, reactivated herpesviruses, and autoimmunity.
Many researchers, including our team, believe the SARS-CoV-2 persistence hypothesis to be one of the strongest - in spite of the negative clinical trials to date.
Makin interviewed Dr. Amy Proal of the Polybio Research Foundation, who explained in particular why NIH RECOVER’s large 25-day Paxlovid trial may have failed.
Specifically, Dr. Proal noted that the trial did not have any biomarkers to know ahead of time which patients actually had SARS-CoV-2 persistence. (This is true of all Long COVID trials to date).
Not all Long COVID patients may have persistent SARS-CoV-2, so if you include high numbers of those patients in a trial designed to clear SARS-CoV-2, it will diminish whatever signal you’re likely to see.
In addition, 25 days may simply not be enough time to see results, as other chronic viruses such as HIV and Hepatitis C can take months of antivirals to meaningfully control the infection.
Makin also spoke with Dr. Michael Peluso of UCSF’s LIINC program, who explained that their team has moved away from searching for the virus in blood, where it can more easily be destroyed by the immune system, and are instead focusing on obtaining tissue samples from potential reservoir sites deeper in the body, where the virus could hide
Detecting the virus and developing biomarkers for these sites is much more complicated, and will take time. However, Dr. Peluso said that he remains optimistic, and things that in the long run, RECOVER’s extensive tissue-banking efforts will pay off.
Makin also highlighted the work of Dr. William Pridgen, who’s been pioneering the use of antivirals for both reactivated herpesviruses and persistent SARS-CoV-2, with some dramatic successes in case studies thus far. Dr. Pridgen is currently overseeing a Phase III clinical trial of herpesvirus antivirals for fibromyalgia- a condition which many think of as purely nervous-system based, or even as a result of psychological factors.
Finally, Makin also outlined some of the newest potential treatments and trials for autoimmunity, including immune adsorption (which has shown success in case studies, but not a placebo-controlled clinical trial) as well as the immune suppressant daratumumab- currently the subject of a clinical trial in ME/CFS.
A bit of hope for you all: Makin quotes Dr. David Putrino as saying the field is approaching a tipping point.
“We’re really starting to understand what’s going on,” (Putrino) says. And researchers are “bringing industry into the space, which always accelerates things”.
We really appreciated this great update, and the fact that Makin is highlighting these infection-associated (and, in many cases, infection-driven) chronic diseases for a mainstream scientific audience.
Check out the piece in the link above!
Paywall-free version here: https://archive.ph/7Wlqo