u/ffffffff-als

Friend of mine just got the informed consent paperwork for SPG302 (now called "Tazbentetol"). The mechanism of action seems really neat in theory but I am wondering if anybody has had any experience on this drug and what your anecdotal evidence is about its effectiveness/lack thereof?

When I read through everything it seems like it's shown a lot of promise in the Alzheimer's space, but obviously that doesn't translate to ALS because, well, those aren't the same thing. I'd love to know if it's been safe anecdotally and what effect, if any, it has had on progression. Thank you in advance.