Azoospermia, 31M, recent fever, recent heavy colchicine use, pretty bummed
Hello everyone!
I went to urologist last week just for checkup, and mentioned we were thinking of having a baby in two years. Me and my wife (28F) never tried to conceive and always protected. Doctor told me I could take a spermiogram just to have peace of mind. I did and the results came back as azoospermia. We are devastated for the last several days with my partner.
Looking for anyone whose case overlaps with mine, especially on the fever timing, colchicine, or the cyst. Full numbers below.
My questions:
Anyone whose first SA happened to fall 3–6 weeks after a significant fever and came back azoospermic? What did the 3-month recheck show?
Anyone with azoospermia who was on colchicine (gout, FMF, Behçet's) and stopped? Any change at the 3- or 6-month SA? Google is not helpful, but the andrologist told me it could be contributing significantly.
History
Bilateral undescended testes as a child, treated with a short course of hCG injections at age 5–6. They came down after 10 shots. Gout since 19 (father has it too). Using Colchicine flare-only for 12 years, never daily, but frequent flares and heavy use over the summer.
Stopped after azoospermia result (at the recommendation of the doctor).
I also had 39 °C fever with rigors on 6 Sep 2026 and had to go ER. It was a pretty bad cold and resolved after one week of antibiotics.
31M, 83 kg, no smoking, no alcohol, no prior surgery.
Semen analysis (30 Sep 2026, 3 days abstinence, 24 days post-fever)
Volume 1.25 mL, pH 7.5, azoospermia. Lab centrifuged and examined in detail: still zero. Repeat scheduled 8 Oct.
Hormones (2 Oct 2026, 26 days post-fever)
FSH 14.9 (was 11 in 2021)
LH 5.77
Total T 744 ng/dL
E2 27.6 ng/L
Prolactin 4.91
Scrotal Doppler (1 Oct 2026)
Testes 9.3 mL left, 8.6 mL right. Everything normal.
The cyst
I have a "Midline prostatic cyst" at the base of the prostate, first seen incidentally on MRI in 2019 at 12 mm ("ejaculatory duct cyst?" note by radiologist), but after seeing the results the andrologist told me it is most probably not the cyst.
Pending: karyotype, Y-microdeletion, repeat SA this week, clean SA in January. Micro-TESE after that if still zero.