Thalassemia + MPN?
Age: 38
Gender: Female
Doctor's specialty: Family doctor (awaiting referral)
Reason for suspected MPN: Chronic elevated WBC and platelets
How long have blood counts been high: At least 1 year
| TEST | Flag | Result (May 1, 2026) | Result (January 8, 2026) | Units |
|---|---|---|---|---|
| WBC | HI | 16.3 | 12.7 | x E9/L |
| RBC | HI | 5.76 | 5.5 | x E12/L |
| Hemoglobin | 129 | 126 | g/L | |
| Hematocrit | 0.407 | 0.39 | L/L | |
| MCV | LO | 71 | 72 | fL |
| MCH | LO | 22.4 | 23 | pg |
| MCHC | 317 | 321 | g/L | |
| RDW | HI | 15.4 | 17.3 | % |
| Platelet Count | HI | 599 | 578 | x E9/L |
| Neutrophils | HI | 11.3 | 8.4 | x E9/L |
| Lymphocytes | 3.5 | 3.2 | x E9/L | |
| Monocytes | 0.7 | 0.6 | x E9/L | |
| Eosinophils | 0.6 | 0.3 | x E9/L | |
| Basophils | 0.1 | 0 | x E9/L | |
| Immature Granulocytes | 0.1 | x E9/L | ||
| Nucleated RBC | 0 | |||
| WBC Morphology | NORMAL | |||
| RBC Morphology | Slight Microcytosis | |||
| Platelet Morphology | Increased moderately.sp\Platelet clumps. Interpret platelet count with caution |
Additional info:
* Thalassemia (NOT CONFIRMED)
- awaiting results of hb electrophoresis (delayed)
- NOT from the "typical" thalassemia backgrounds (Mediterranean, African, middle eastern, etc)
* IIH in 2015/2016
- papilladema on visual exam (this has since resolved)
- normal lumbar puncture, CT and MRI
* Obese
- 308 lbs
- have intentionally lost 42lbs since beginning of January and plan to lose at least 100 more
- eating roughly 1700 calories daily
- no longer pre-diabetic (a1c is normal)
* Blood pressure: 115/85 (down from 135/92)
* Heart rate: 95 (fluctuates but usually a little higher than normal)
* Pulsatile tinnitus (for at least 10 years)
* Dizziness on standing
- usually in the afternoon and evening
- vision blacks out but comes back after 3-5 seconds
- have not passed out but felt close
* Headaches (for at least 10 years)
- get bad headaches sometimes that are usually behind my left eye
* Morning nausea (for the last 6-12 months)
- occasional morning sickness, sometimes throwing up bile
- comes on very suddenly and goes away pretty quickly
* Vape THC at night
Daily medications:
- Cymbalta 90mg
- Vyvanse 40mg
- Reactine
- multivitamin
- vitamin d
- magnesium
- melatonin
Last year it was suspected that I had thalassemia so I was given an order for more bloodwork. I took my time because it seemed like such a minor diagnosis.
My family doctor called me in recently to discuss my blood work. He was concerned that my WBC has been elevated and climbing for over a year, along with my platelets. He mentioned chronic lymphocytic leukemia or another MPN but was really unsure and is referring me to an internist for a work up.
Going in suspecting thalassemia and coming out with a potential cancer diagnosis was so out of left field.
Since I haven't been to the internist yet my mind has been all over the place. If there's any other relevant information needed, I'd be happy to share it!
Thank you so much to anybody who reads this. ♥️