u/mnnyr3

Hello everyone,

I wanted to make a post here to get some valuable first hand accounts as to help both my father and family and I with understanding my dads condition.

He is scared of doing chemotherapy and feeling sick and all the side effects. We are looking into the best treatment options like daraxonrasib, dendritic cell therapy in Germany and even anecdote evidence about drugs like Fenbendazole, Ivermectin and Mebendazole. Does anybody have experiences or advice on what the best way to go would be? How quickly does a person start to go from feeling great to feeling bad? Will chemo take a good healthy person and turn them into an unhealthy person? Money isn't really a problem, we just want the very best treatment possible, know exactly what we're up against so we make the best decisions and pray for the best and hope he is one of the few that beat the odds.

My dad reasons, he feels great right now, barely any pain/just some discomfort/back pain so why take chemo and feel like crap? My reasoning to him is that if he doesn't slow down the cancers growth, eventually the tumor will get too large and start to give him many problems, and then it will be too late to go backwards. My understanding is that if he takes chemo now, he can slow down, or even stop and shrink the tumor and he can "feel like he does now" for a lot more months, before he starts to feel sick. We just want him to have the longest life with good quality life. I'm not sure if chemo will extend this for him or start to make him feel like crap now. If that's the case he would rather not.

Has anybody taken daraxonrasib or daraxonrasib + chemo + immunotherapy?

What about dendritic cell therapy in Germany? is it worth it to travel there or another country who is better at pancreatic cancer treatment? He likes this treatment a lot because there's really no side effects and it makes your immune system attack the cancer.

Has anybody gone to Memorial Sloan Kettering? We are attempting to get on a new clinical trial for daraxonrasib as a first line treatment, instead of as it's been used for patients who had already done chemo first which had stopped working.

What are the chances he can survive longer than the average? What can we do to give him the best chances? Diet etc? What have been the best case scenarios? I've seen some stories of people with stage 4 live for multiple years and beat the odds. Any advice to give him more time with us or makes his life better would mean a lot.

Backstory:

2 weeks ago, due to a pain near his stomach and back my dad went to the ER to get checked out, only to get sudden news that my dad possibly has pancreatic cancer that has spread to the liver and was urged to see an oncologist immediately and get a biopsy done. He has a tumor in the middle of his pancreas around 2cm large in the middle of his pancreas. The oncologist was certain it was stage 4 cancer as he saw lesions on his liver but needed to get the test done to confirm and get the insurance side of things going to start the ball rolling for treatment as fast as possible. This news hit us hard and we're still processing the news.

We have moved as fast as possible to get dad the best care as possible, we were even able to get an appointment with doctor Epstein at Sloan Kettering in NYC in hopes he could possibly get my dad into a clinical trial for daraxonrasib since the hospital where we're are at (Vassar Hospital) does not do clinicals. The oncologist at Sloan confirmed everything on the biopsy and it is stage 4 pancreatic cancer, exactly as the first oncologist diagnosed. Now it is time to decide on what treatment to do to keep my dad here the longest as possible with good quality of life. We have multiple appointments coming up, both for a follow up with the oncologist who first gave him the diagnosis 7/2, the port install 7/7 and also Sloan asked us to come back 7/8 (cross my fingers it's a promising sign he can get on the clinical trial).

My dad is 66yrs old 5'8 about 220lbs Puerto Rican who is as strong as a bull, always has been. He's the hardest worker in the room and has built a few companies. His health is overall very good for his age and his mind and spirit is very strong and he feels like nothing is going to take him down because he's going to fight it. His dad died at 94 and I thought I was going to have my dad for so much longer, so this has been such a hit to our family to know we are going to lose our dad, especially when we thought he was going to live just as long as my grandfather. It is so painful to think about.

🙏🙏🙏 Thank you! 🙏🙏🙏