u/okaycoolgood

Hi, I hope this is an acceptable question. I hear mixed things about getting multiple covid vaccines in a year, one of them being that "immune fatigue" will make it so you don't respond to them. I am not looking for medical advice/trying to follow the rules of the sub here, but just curious because I have an autoimmune disorder and am on immunosuppressants and I'm sick of getting covid every year right after my yearly vaccine wears off (like clockwork!). theoretically, what happens if you get 2 - 3 covid vaccines a year?

extremely unlikely/specific request, but algernon cadwallader played a version of revelation 420 at ruba club last night (from their album from last year) that i liked sooo much more than the recorded version on the album. was wondering if anyone managed to capture it!

I have moderate Crohn's somewhat controlled with skyrizi. i'm currently flaring and on budesonide in addition. i looove my skryizi, she's not perfect (clearly) but she does *almost* enough.

i really want to avoid having to switch to a TNF blocker bc of MS concerns (long story), but my GI has been discussing making the switch bc i've flared a bit more than we've liked on skyrizi (not nearly as bad as before i started it tho). i've been reading a lot about how glp-1s are great for inflammation.

i know there are posts on here about success with glp-1s for crohn's, but i wanted to ask specifically about 1) microdosing them - i don't want to lose too much weight, as i'm at a healthy weight already and 2) taking them if your main flare symptom is constipation and bleeding. i get constipated, then i have rectal bleeding because of it. i know that glp1s slow the tract so they cause constipation, but i was wondering if this would be counteracted by the anti-inflammatory effects, since my constipation is *caused* by inflammaiton.

yes, i will talk to my doctor about this more too. but the research is so nascent that in the past she's expressed that she's not so sure either. so just wanted to farm others' experiences.

i'm probably going to guinea pig myself for this regardless and see how it goes as a last-ditch effort to stay on skyrizi and maybe control my inflammation even better (i also have arthritis secondary to crohns). thoughts?

I have Crohns treated with skyrizi and a current minor flare (no clinical symptoms, but some inflammation on scope) we're treating with budesonide.

last week I yanked a hangnail like an idiot and a few days later I got a NASTY paronychia (nailbed infection). I went to urgentcare and he said "go to the ER right now if you want to keep that finger." Great. I go to the ER and they say it's not bad enough to warrant IV vancomycin (even after I beg and plead for non-oral antibiotics bc of my Crohns). So they drain the wound and send me home with 4x-a-day keflex (cephalosporin) and 2x-a-day bactrim. I'm sooooo terrified this is going to worsen my current flare. Should I try to switch to doxy or something gentler? I have no idea what to do. I don't want to lose my finger or get sepsis, obviously. But I also don't want to end up with an even-worse flare (I took clindamycin 3 years ago and had the worst flare of my life).

Has anyone here taken this dose of cephalosporin and been okay? I need some reassurance right now i think 😞

I'm writing this as someone diagnosed with Crohn's 3 years ago who is now pretty scared I may also have multiple sclerosis. I'm shaking even writing this because I feel like I'm going to "manifest" it happening. (Haha.)

I got a scary test result today and I want to know if anyone else has ever had this:

I was referred by GI to the neuro-ophthalmologist because I've been having migraines (have gotten them my whole life actually), some bouts of blurry vision sans headache (that's the scary symptom), and frequency with urination (also bad). On my Optic Nerve result it said I have "bilateral temporal thinning in the GCC (ganglion cell complex)." Dr. Google seems to think this means I've had optic neuritis in the past, which is pretty specific to MS.

So I'm here asking, pleading, has anyone had this with Crohn's, rather than MS? I know Crohn's begets MS, but dear god, I don't think I can mentally handle another autoimmune diagnosis.

i've had crohn's for a couple years now and have managed to generally avoid steroids. i had to go on prednisone for just 2 weeks a few years ago and that wasn't too bad--some issues with my eyes and sleep but otherwise ok. i also did 2 weeks of methylprednisolone a few years back and that was totally fine too, no side effects. but these were short, low dose tapers.

i just started an extremely demanding, stressful new job, moved to a new state, and have had some other major issues in my personal life. so i started flaring. i'm really frustrated, i thought i had things under control but apparently i do not.

i'm currently on skyrizi every 8 weeks, but my doctor is bumping me up to every 6 weeks and simultaneously starting me on a budesonide taper. I'm going to be doing 9mg for 3 weeks, then 6 mg for 3 weeks, then 3 mg for 3 weeks. So a total of 9 weeks.

I'm really scared. How will this--in combination with the more frequent skyrizi--affect my mood? My weight? My immune system? Will I get moonface? Will I get the classic steroid rage? what about my sleep? I work with patients in a clinic, should I start masking all the time?? I'm so scared yall. looking for some realistic responses but also maybe some reassurance. my doctor said that this drug is less systemic than other steroids but it still can have systemic affects. so i dont know what to expect.

if it says "presale happening now" but then when you click that link in ticketmaster it says this, does that mean the day 1 of presale is sold out? i'm not tech savvy and i've never bought tix via a presale before lol

ugh. i literally was being rolled into anesthesia for a procedure begging them to let me have my phone for 1 more min so i could buy a ticket and i still missed out :'( i'm so bummed

https://preview.redd.it/rzmnqtgkz6yg1.png?width=1756&format=png&auto=webp&s=3ce6d1d7a149dc9d521ead3f6f54a618c0732553

I do the miralax + dulcolax prep. I took the 4 dulcolax at 5:30 PM and drank the 1st bottle of gatorade/miralax between 6 and 7 pm. it's now almost 10:30 PM and....nothing. And I don't feel like I'm going to "go" anytime soon.

What should I do? I'm kind of panicking :( This is my 7th scope and this has never happened to me before. When I google it the results say "call your doctor" but um...who has their doctor on speed dial for 10:30 PM calls lol?? Should I take another dulcolax? Drink a little more gatorade/miralax? Ahhhh