▲ 7 r/CHROMATOGRAPHY+1 crossposts

Is a helium leak detector really necessary for GC-MS?

Do you really need a helium leak detector when changing a helium cylinder for GC-MS?

We normally check the regulator and fittings after a cylinder change, but I’m wondering if buying a dedicated helium leak detector is actually necessary for routine use.

Do most GC-MS labs use one?

reddit.com
u/zeydullak — 10 days ago

Whether to choose Agilent 6475 or Agilent 6495D for PFAS?

Hi everyone,

We are planning to purchase an Agilent LC/MS/MS system for PFAS testing and wanted to get some feedback from people with real experience.

Is the Agilent 6475 Triple Quadrupole LC/MS/MS strong enough for EPA PFAS methods such as 533, 537.1, and 1633?

Or is it worth spending significantly more money on the Agilent 6495D because of the higher sensitivity and performance?

We are trying to understand if the 6475 is enough for routine compliance work, or if the 6495D is a better long-term investment for PFAS testing.

Any feedback from labs running PFAS methods would be appreciated.

Thanks.

reddit.com
u/zeydullak — 2 months ago

Where to choose Agilent 6475 or Agilent 6495D for PFAS?

Hi everyone,

We are planning to purchase an Agilent LC/MS/MS system for PFAS testing and wanted to get some feedback from people with real experience.

Is the Agilent 6475 Triple Quadrupole LC/MS/MS strong enough for EPA PFAS methods such as 533, 537.1, and 1633?

Or is it worth spending significantly more money on the Agilent 6495D because of the higher sensitivity and performance?

We are trying to understand if the 6475 is enough for routine compliance work, or if the 6495D is a better long-term investment for PFAS testing.

Any feedback from labs running PFAS methods would be appreciated.

Thanks.

reddit.com
u/zeydullak — 2 months ago