I have AS, have tried other biologics since my diagnosis in 2024, and have now switched to Bimzelx. The injection wasn't as painful as I thought it would be but I feel pretty gross with nausea and a stomach ache, which is on top of my usual slight nausea from a glp.
Anyway, fingers are crossed that this works!
Im not talking about being nervous about being on or taking a biological. Ever since I started bimzelx my anxiety gets set off by EVERYTHING.
Anybody else getting this side effect? Im 2 weeks in on my first loading dose and my anxiety has been almost non stop ever since. Its exhausting.
For those who are taking a biologic and a glp-1, do you take your shots on the same day of the week or do you spread them out?
I’m taking Bimzelx and just picked up my first round of Zepbound. I think I’d prefer to take them on the same day, but would like to hear others’ experiences before I decide. Thanks!
Long story short: I have HS and was on Humira for a year until now. It wasn't helping at all with my condition so my derm swapped to Bimzelx. The idea was there for months, but he took the decision now.
I've been reading other people's thoughts about it since he mentioned it, and from everything I read, the most common word was PAIN. Like, it hurts very bad. I was already sweating, panic, anxiety and whatnot while thinking about this day. All the stuff I could imagine about how badly it would hurt.
Today I had my first dose, a 320mg pen (I'm Spanish, if anyone cares). I was ready for the unbereable pain, the doctor told me to pinch some meat on my tigh and to go ahead. I did so.
It stings? Nope, completely normal injection sting, you notice it but doesn't hurt. Did it burn? It didn't... for the first 3 seconds or so. After that, it burned, like a lot, but a completely bearable pain for anyone like us who face such painful conditions. After 5 seconds of burning it started to fade away, and the last 5 seconds or so no pain at all.
Idk if I just had luck, or pinching actually did something (never pinched with Humira bit the very first day). I just hope that the rest are as bearable as this one.
TL;DR: it wasn't as bad as 90% of the posts I saw on the sub are claiming. And it's not like I have high pain threshold. I just wanted to post my story to help anyone who is having a real bad time like I did thinking about the pain before starting on Bimzelx.