r/BritInfo

( https://www.alzheimersresearchuk.org/news/dementia-is-the-uks-biggest-killer-we-need-political-action-to-save-lives/ )

Hello! I'm not british although I have a fascination for learning about neurodegenerative diseases and I've got to say I feel like most people don't really talk about them, despite how severe the issue is.

Most people are talking about cancer and whatnot, and whilst they are indeed a huge issue, I feel like a lot more research should go to identifying the causes behind dementias and how they work, they deserve to have more awareness raised about them.

Did you know roughly a million people in Britain have dementia? With Alzheimer's disease representing 60-80% of cases. Currently, there are thousands of people as we speak affected by the terminal stages of dementias, in which the patient is bed ridden, completely lacks motor coordination to the point they can't move, can't think and can't talk either. At that point, all one can do is wait for the point where they aren't even able to eat, which is why people die from it.

Dementias are *all*, progressive, terminal diseases. There is no such thing as living with dementia, only dying with dementia, because all dementia patients will eventually be in a vegetative state where they are immobile and barely even conscious.

I'm not an expert, but it seems dementia is not deeply understood scientifically either. Correct me if I'm wrong but most of our understanding about dementia is about Alzheimer's, and we mostly know about the byproducts of it, such as amyloid plaques and neurofibrially tangles. We can't know for sure what's causing the buildup, nor if their buildup is what is actually killing the neurons.

We don't know which specific biological process causes it, either. We only know it's genetic and risk factor related and the genetic factor is only the cause for certain types of dementia, which is wild.

If this disease is the leading cause of death for brits, I think more people should know about its full extent, at least, and that we should focus even more on research about it. It's a huge health issue, but we don't even know the exact cause and tons of important details, and that's just crazy to me.

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