r/HelusPharma

Again, not exactly sure of the specifics, but it seems two newly appointed executive officers were given 425000 shares if they stick with the company through 2029

Helus Pharma Appoints Regina Donohue as Chief People Officer and Suresh Durgam, M.D., to its Scientific Advisory Board

07:30:00 AM ET, 08/18/2026 - GlobeNewswire

Helus Pharma Appoints Regina Donohue as Chief People Officer and Suresh Durgam, M.D., to its Scientific Advisory BoardGlobeNewswire

Former Intra-Cellular Therapies, Inc. (“Intra-Cellular”) executives bring complementary experience in organizational scale-up, central nervous system (“CNS”) drug development, regulatory approvals and commercialization

Ms. Donohue is the former Chief Human Resources Officer of Intra-Cellular, where she led the company’s people strategy and human resources infrastructure as it transitioned from a clinical to a commercial stage organization of 1,000+ employees

Dr. Durgam is a recognized CNS drug-development leader who played a pivotal role in securing multiple U.S. Food and Drug Administration (“FDA”) approvals for CAPLYTA® (lumateperone), including in schizophrenia, bipolar depression and adjunctive major depressive disorder

Appointments support Helus Pharma’s continued growth, scientific leadership and preparation for potential commercialization

HELP Q2 filings show strong institutional accumulation, though no evidence of access to blinded Phase 3 data.

Adage Capital increased from 700K to 3.06M shares (3.29M incl. warrants, 5.29% ownership). Other new/increased holders include SIO (1.3M), Logos (750K), DCF (743K), Sphera (~634K), Nan Fung (~527K), Rosalind (425K), and Boxer (150K), totaling ~6.9M shares added.

Fintel shows institutional longs up ~2.62M shares (+8.95%), with 63 buyers vs 14 sellers. Notable trims: Sirenia (down 648K common, still long warrants), OrbiMed (still 3.27M), Deep Track exited common.

Warrants: June raise was common-only; $8.14 warrants came from Oct 2025 financing. 189K were exercised on Aug 10 (~$1.54M), leaving ~9.22M outstanding.

This morning strengthened the pre-Phase III HELP thesis on two fronts.

Recent ownership filings show meaningful institutional accumulation occurring behind the scenes, including Adage Capital crossing the 5% threshold with 3.29 million shares, alongside substantial positions from sophisticated healthcare and hedge-fund investors such as OrbiMed, Venrock, Millennium and Eventide. This helps explain some of the recent share-price appreciation as institutional investors increasingly underwrite the probability of a successful APPROACH readout rather than simply speculative retail momentum.

Today’s financial update was equally constructive. APPROACH enrollment is complete, Q4 2026 topline guidance remains unchanged, EMBRACE and EXTEND continue advancing, and the completed DDI study further supports HLP003’s commercial positioning as an adjunct to existing antidepressants. Helus ended June with $166.4 million in cash following its $50 million institutional financing, substantially reducing pre-readout financing risk.

Taken together, there is no evident deterioration in the clinical thesis, timeline or financial position. Instead, institutional ownership is becoming more visible, the balance sheet is well funded through the pivotal catalyst, and management continues executing toward the Q4 Phase III readout.

Let’s fucking go!

Why does the earning date keep moving by one day?

So anybody else going all in on psychedelics? Well I have and I have been here since 2020. First made a killing from Mindmeds run in 2021, then lost 90% and was struggling for almost 5 years. I was unemployed and almost had to sell it all to cover my expenses when it was at all time low.

But I never lost faith because I personally know how much they can help. So then they started to recover and I started buying more. Now my portfolio is back to those 2021 highs and I am feeling great.

Currently my portfolio is made from:

Helus Pharma 42.5%, Compass Pathways 24%, Definium Therapeutics 23.5%, AtaiBeckley 4.5%

In the last 1 year my portfolio is up +242% and +20858€ 😎

I am so glad that in these modern times I can participate in the US markets from my own couch. One thing is for sure and that is you guys really know how to make money there! It's very different here in Europe. Anyway I still believe we are incredibly early and we can really make some life changing money from this run. Just have to play our cards right. Personally I am betting now in Helus the most because their market cap is ridiculously low compared to other big names. Gotta take risks to make money! Still have a very big bet in Compass and Definium also (but already made 400% on both).

So what are your thoughts? How much is your portfolio up last 1 year? And what are your biggest ownings in the space. Anybody else going all in? Would love to hear your stories. Anyway cheers to all longs and hold tight because it's gonna be a wild ride!

Ugly day, no question. Down about 14% after running from the $7s to almost $12 in a very short period. But I don’t think the bigger picture changed much. This looked more like a hard momentum flush than some fundamental breakdown: failed push at $12, profit-taking, stops getting hit, short-term traders bailing, and probably some option-related hedging effects with the August expiry coming up.

There’s also a reasonable possibility that some warrant holders exercised around the $8.14 strike and sold shares into the strength. If that happened, it would add temporary supply without necessarily meaning those investors are bearish. They could easily monetize the shares and keep Q4 upside through December calls or other positions.

Technically, the stock finally got the reset it probably needed after going almost straight up.

Wednesday August 12

https://ir.helus.com/news-releases/news-release-details/helus-pharma-participate-canaccord-genuity-46th-annual-growth