r/researchchemicals

Question for those who have already had the purity of research chemicals purchased tested: what were the results? Did you have any unpleasant surprises?

Hi almost every i go at a rave i don't want to endup on 3mmc(or whatever cath it really is) but as soon as i have the opportunity to take a bump from someone i do it without thinking and it kinda fucks me up because of the harsher comedown and craving

anyways how do i deal with that compulsion? it's like i can't even think it just takes me over, i'd like to go to raves sober, i don't have that compulsion with mdma but it's really hard to deny a 3mmc bump from someone

it ruins my night every time i come out of it looking back regretful as if i didn't have a good time even if i did and it fucks with my mood, motivation and anxiety for the next week even if i have NAC 5-htp and benzos

the worse is when i endup with a bag home or at an after...

i don't want raves to be a net negative on my life..

While watching a YouTube video about 3-me-pcpy(from KhaoticK) I read a comment which struck me, I will post it here:

“My go to dose was 50mg. Effect wise it was top 2 disso for sure. You can definately hole if you push it, it has the most beautiful hole ever i didnt expect that. But beware its really neurotoxic, you probably didn’t feel it because you’ve done one dose I suppose but when i did it more i actually got permanent brain damage from it recently. For reference i did way more opce in the past and never got this. Cant do any dissos for some time because of that “injury””

This user even talks about permanent brain damage. 3-me-pcpy is relatively new , and has been researched much less than the other dissos.

Has anyone got any experience or knowledge, especially regarding the neurotoxicity.

Thanks a lot guys.

First of all the experiences on this sub vary so widely. No one’s really saying it’s the best stim ever but a lot of people actually enjoy it (not just that they keep having more cause it’s fiendish). Some people can sleep two hours after last dose, some say 6-10 at least. Some people say you don’t even feel anything fun it’s just compulsive, even from the first dose and others get good euphoria from it. Is it different batches causing this or does nep just react very differently depending on the person?

I’ve also seen an insane amount of posts on how if you vape it you won’t be able to put it down until the bag is done, no one can do one or two doses etc etc. To be fair I do have a pretty good history of self control but I don’t think I’m immune to fiending, but I’ve been trying out the vaped route in the last few weeks, and it’s really not like people say in my experience. I find it a slightly cleaner high than other roas and I get significant stimulation for at least an hour and a nice smooth drop off for the next two hours but still being high and not needing to redose every 20 minutes. Of course there’s cravings in between but for example I had no problem planning to do one dose vaped and then not having anymore for the rest of the day and what I have is definitely NEP. Anyone have some insight on what these differences could be caused by?

need advice i know how to i’ve done 4mmc many times before, just never smoked it

im guessing i need less than snorting? or is this wrong. my plan is to smoke 100mg and see what happens. is this stupidly high dose or just right?? thanks

Got 5 grams from a trusted vendor back in February 2026.
Beige powder, has close to no taste just a bit funky.

(Important to note that while i had no stimulant tolerance, i was on and off Seroquel 300 mg at that time and took caffeine and nicotine daily.)

Took about 100-150 mg the first time (oral), 1 hour come-up, very soft, definitely mood enhancing, no rush (oral), feels really close to high doses of caffeine but more dopaminergic and no cardiovascular strain felt.

I went up to 550mg orally which was very peasant and fitting as a practical stimulant, still I'd consider it a very light substance, can easily fade in the background (which in my case was kind of the point, it helped me focus very well)

Hard to say exactly the duration as the comedown happens progressively, no heavy "crash"

I will say though that it was between 2-7 hours duration with some residual stimulation lasting sometime up to 10 hours with higher doses.

Was a nice experience overall and i finished the 5g in about 12 days, Wouldn't go as far as saying it was "euphoric" but i liked it and would take some again, prolly depends on the person and i only tried oral ROA.

Excited to try the analogs in the future, heard some good feedback on 3-FTL , and Thozalinone in itself is a very cool molecule (was used as an antidepressant in Europe haha).

Will make more RC reviews if this one feels useful.

Cant believe I’m making this post but my best friend overdosed and died sunday after basically live texting me a Mirogabalin trip report Saturday night.

Its lowkey too painful to keep reading the texts but he staggered 3 30mg doses to begin with, then did 50mg sublingual 2 hours later, then insufflated an unknown amount about an hour after that. It seems he was under the influence of Rilmazafone Friday, and possibly saturday morning.

Anyone who could give me an understanding of typical doses of mirogabalin would be appreciated because this really comes out of nowhere. He was extremely smart 130+iq with a very very strong understanding of pharmacology and chemistry. He was super tolerant to all benzos and would do absurd doses all the time but only ever needed to go to the hospital for stuff like Tiletamine and Brorphine overdose. He was 6’1 and probably 200lbs.

I’m a former addict and understand how these things can just come out of the blue but that doesnt take away from how un fucking believably painful this is. BE CAREFUL and don’t let this happen to you.

I’ll try to find his reddit and update this post if i need to for more context.

Couldnt find his reddit but here’s a song he made, one of my favorites by him soundcloud.com/socialdefeat/weed-song-for-420

So I am going to a massive festival soon, goal is to get as mashed as possible, i’m highly experienced with drugs and my plan is to take 800mg pregabalin as i get off the train and arrive at the city its happening at, then as soon as i get into the festival drop 2 2cb pills (sold as 25mg, likely around 10-12mg) and then do bumps out of my home made pink cocaine mix every now and then whenever I want a boost (1 crushed 2cb pill mixed in with a gram of ket) and redose by double dropping more 2cb pills every few hours whenever i feel it wearing off. I have 6 2cb in total that I plan on doing. After the festival (12+ hours) there’s an afterparty with more rave music and psytrance, dnb and hardtek and shit and when my 2cb has ran out and pregabs mostly worn off i plan on dropping another 400-600mg pregabalin but this time taking an acid tab or two (sold as 250ug, most likely 100-150ug) at the same time (i will be bringing 3) my mate also is bringing 4mmc (mkat) which I will likely be doing small amounts of here and there (he’ll give me wham lines) most likely while im on the 2cb and probably on the acid, and finish off the pink cocaine mix throughout the whole night in small bumps. I am also likely going to have 2-3 pints of alcohol but no more as I am not a drinker and a lightweight to alcohol.

How does this sound as a plan? anyone had experience with similar combos? anything to note or any recommendations for max hedonism? I will be taking magnesium glycinate too as i enter, i will have xanax as a trip killer on hand as well and lots of electrolytes

Have ghb, carisoprodol, or etizolam to help with sleep after if needed

Edit for clarity: by structural I mean chemical

like the title says. im taking Gaviscon to jelp and will not be eating stuff im not allowed ​or drinking alcohol. just wondering if this is ok? would only be 1g 3mmc.

Hi I was wondering if there is any site where people share their Lab results for tested drugs? Maybe even with the vendor they bought from?

I know kykeon.

Thanks in advance

I have a friend on a very high dose of a former research chemical Benzo - Diclazepam. He is on roughly 20mg per day. He bought these online before they scheduled them and has been using them for years. He has severe health problems and cannot go to a normal treatment center. All his health problems have been documented by doctors, but obviously he is not prescrbed this medicine since it is a RC. He has been on it for years, but is running low on supplies. He has propsensity towards seizures, has severe hormone issues, etc. He is basically bedridden from other health conditions, which means he cannot go to the doctor. He is in his early 30s. He is running low on supplies, the research chemical is now a controlled substance and regular health professionals might be scared off by the high dose.

He tried one telehealth addiction service, which after asking questions for an hour, ultimately said they couldnt help since he was on something "illegal" and he would need to go to an in-person facility, which obviously isn't possible/

Any advice on the type of doctors to seek out or any other potential options here? Thanks

Very important importance information pls

Ive been on a lowish dose of pyrazolam for the last 50 or so days, went from around 0.7-0.8mg a day down to about 0.4mg by now. Had a few ups and downs in my dosages so my „taper“ up to now has been inconsistent to say the least.

What’s my best approach for getting rid of the last few mg? Can I just reduce by 0.02mg daily until I’m done or is that too rapid a taper?

Like sounds like a good idea to have people using substances document effects over time to get some info maybe try to get some safe use resources

Hey everyone,

Crazy story from this weekend. I sent a long, detailed email to one of the biggest European RC shops. I wanted to bring up two major issues we often discuss here: the overpriced NB-DMT blends relative to their actual efficiency, and the bioavailability issue with 5F-MET sold as a fumarate salt (which is a pain to vape).

To my absolute surprise... The owner replied to me personally, and their lab literally spent the weekend working on our feedback! Here are the updates, and we need your input for the next steps. 👍

I explained to them that NB-DMT is much less "efficient" per milligram than classic N,N-DMT due to the protecting group (Boc), and that their current pricing just didn't make sense. The owner totally agreed with the criticism. Result: he talked with the lab, and they just dropped the price by 12% across the site while waiting to produce a larger batch that will be even cheaper ! Boom.

For the 5F-MET, we need your ideas! Following my email about 5F-MET fumarate (not suitable for vaping), the lab spent the weekend synthesizing a batch of 5F-MET in Freebase form. The good news: the purity is excellent. The bad news: the molecule in its freebase form doesn't crystallize well. It is stable, but it turns into an extremely viscous liquid (like a thick oil or paste), which makes it a nightmare to handle for us in standard baggies.

The shop owner literally asked me: "How would the community prefer us to produce/package this so it's as user-friendly as possible?"

They are thinking about making disposable/pre-filled vapes, or selling it in a diluted form. But I figured I'd ask you guys to gather the best ideas from the sub and send them back 😏

How would you prefer to buy and handle a highly viscous freebase tryptamine?

In a dropper bottle, pre-dissolved in PG ready for DIY e-liquid?

As "Enhanced Leaf" (infused onto neutral herbs, ready to be smoked or vaped in a dry herb vaporizer) ?

In small silicone/glass jars like BHO/Dab wax, to be used with a dab rig?

Any other brilliant ideas?

Drop your best suggestions in the comments, I'll make a summary for the shop in a few days !

(PS: Please don't ask me for the name of the shop in PMs, let's respect the sub's strict no-sourcing rules so this post doesn't get taken down). ✌️

So I wanna know where does BROMAZOLAM rank in potency I have 900 4mg pressed bars of BROMAZOLAM and I’m trying to find the best way to wean off it safely. I also have Valium Xanax and Klonopin now please only respond if you really know your stuff I know there’s not a lot of accurate information due to it being an RC benzo, but just around

I mean it's nice they told us but...