Modern humanity has 200 years to make the closest thing to a space marine that is possible.
Humanity is hell bent on doing this, everyone focused on this task alone.
We can use alternative materials/tools to go around the more magical scifi aspects of the space marine. A lasgun and a one-handed 50cal are gonna have similar effects. Let's not forget the high likelihood of humanity improving its tech in the timespan.
Second challenge: How might humanity outfit this supersoldier to be able to win against a space marine 50% of the time?