Tesamorelin water retention — did it eventually go away for you?
I’ve been on Tesamorelin for around 3 weeks now and I’m curious about other people’s experiences with water retention.
I initially started at 1.5 mg, which was clearly too much for me. I then dropped to 1 mg and I’m currently down to 500 mcg.
Since starting Tesa I’ve gained around 3–3.5 kg / 7–8 lbs, and I’m pretty sure the majority of it is water. I’m very active with running and strength training and I’m currently in roughly a 500–1000 kcal daily deficit, so actual fat gain doesn’t really make sense.
The frustrating part is that I was in really good shape before starting. Now, despite still being lean underneath, I just look and feel a lot bulkier and softer from all the extra water. I can also definitely notice the additional bodyweight when running.
I’ve read a lot of different experiences.
Some people say the water retention is normal during the first few weeks and that you just have to push through it, with things starting to improve around weeks 3–4 or shortly after.
Others say they held the extra water for basically the entire time they were on Tesamorelin and only dropped it after stopping.
If the water starts coming off over the next couple of weeks, I’d be totally fine continuing. But if I’m going to hold an extra 3–4 kg the entire time I’m on Tesa, I’ll probably stop because it negatively affects both my look and my running.
For those who experienced noticeable water retention on Tesamorelin:
Did it eventually go away while you stayed on it? If so, around what week did you notice it starting to drop? Or did you hold the water until you discontinued it?
Would really appreciate hearing actual experiences, especially from people who had a pretty significant weight increase in the first few weeks.