▲ 6 r/Physiology+3 crossposts

T/F: Insulin helps store energy for later use.

I was on YouTube the other day, and I saw a poll asking this question. Somewhere close to 65% chose true, and I am a bit confused on why it is so controversial. I personally think the statement is true, but I want to know why this could be argued false.

The rest of this will be my reasoning for true:

Basics: I see energy here as referring to energy available for cellular use during a fasting/post-absorptive state. I see these energy storage molecules as triglycerides/fats (primarily), some glycogen, and some protein.

Insulin is a peptide hormone released from pancreatic cells in response to increased plasma glucose levels. Insulin binding to its receptor initiates a kinase cascade that ultimately promotes anabolic processes like lipogenesis, protein synthesis, and glycogenesis. This also translocates preexisting, vesicular GLUT4 transporters to the plasma membrane, allowing for an influx of glucose. I see how this may transiently increase metabolic processes and energy demand (because synthesis would require energy), but the final products of insulin signalling are the storage form of the major macromolecules.

I tried to find the answer in the comments of the original post, but the most liked comments were all saying that the answer was false. Please help me understand why/if my understanding is wrong.

reddit.com
u/Afraid-Topic-4886 — 4 days ago

Clinical Medicine Help

I am in the middle of didactic year and am struggling with Clinical Medicine. Typically, I would just rely on PowerPoint presentations for my initial exposure to new material, but my program relies heavily on guest lecturers (not all of my program's professors are "experts in the field" for their content section). These guest lecturers are hit-or-miss at best; the lectures themselves are okay but the PowerPoints are often unorganized, too thorough or not thorough enough, or not posted until 5 minutes before the scheduled lecture so I have no time to preview.

My professors have encouraged reading Current Medical Diagnosis and Treatment, but the book is the same way. It's super disorganized; on some things it goes into the discrete molecular mechanisms, and on others it doesn't include the epidemiology, 1st line treatments, or important diagnostic findings. I have tried reading it, but I often end up feeling confused and like I wasted my time.

What websites, study materials, or textbooks would you suggest for clinical medicine?

reddit.com
u/Afraid-Topic-4886 — 1 month ago