[Primer] 2005. Aaron and Abe ruptured spacetime in their initial experiment in the garage.
In the second half of Primer, Abe and Aaron start using their discovery to travel back in time leading to a tangled web of cause and effect that starts an unravelling of spacetime with clear signs of divergence in the timeline. (Abe hears a different version of events on a recording of a conversation that he is witnessing on the basketball court). A lot of people have tried to make sense of this half of the film in the last 20 years. (Despite the film telling us “the permutations were endless”)
At first it appears that this fracturing resulted from them using the machine for time travel resulting in duplicates, paradoxes and broken symmetry. But I think they actually caused a rupture much earlier in their initial test with the weeble. They first try the machine using a plate. (Not quite sure exactly what that means). When they do this, they notice the weight of the weeble starting to drop. Excited by this progress, they decide to move from the plate to the box. (Again, I'm not quite sure what that means, but the specifics don’t really matter here). When they do this, the machine takes off and we get shaking and screeching noises with the two of them panicking until the machine peaks and shuts down. My theory is that this noisy test in the “box” was the first rupture of space time caused by their work. The reason I think this is because of what happens in the next scene. The next scene shows Abe waking up disorientated on the floor of his apartment. If you watch closely it’s a mashing together of two similar but not identical scenes. We hear two variations of Aaron’s dialogue on the phone “Abe it’s 7”/”Abe it’s 7 at night”. We see a messy and non messy version of Abe’s apartment. I think what we are seeing here is a ripple caused by their earlier experiment exposing divergence in the timeline. Given how micro budget this film was, with the scarcity of tape being a particular concern for Carruth, I don’t think it’s an accident that he has these two distinctly different takes added in there. Not retakes but deliberately different takes with variations on the set dressing and Abe’s actions. (He throws a shoe in one take but not the other). That cost them time and money, but he pushed it through because it was important. So I think even if they hadn’t gone on to use the machine the way they did, that initial test “in the box” caused a fistula in time that resulted in Abe’s disorientation in this scene.
(I’m not sure if the "protein growth” on the weeble talked about later was from this specific experiment or if they’d run the weeble through the machine a few more times)