



The Indian queens who modelled for the world's first vaccine: Queen Devajammani Sr. (farthest left), Queen Dowager Lakshmi Ammani (center) and Queen Devajammani Jr. (farthest right) of Mysore state. Painted by Irish painter Thomas Hickey c. 1805 CE.
Following the restoration of the Wodeyar dynasty to the Mysore Throne after Tipu Sultan's defeat by the British, three Queens of the state, headed by the Queen Dowager Lakshmi Ammani posed for Irish painter Thomas Hickey.
This however was not just any other court portrait. It was a political statement to the people of Mysore, that it's Queens were now endorsing the world's first vaccine, for smallpox.
The painting is intended to bring hope and to quell fears regarding the new science. The Senior queen Devajammani (left most) shows pigmentation around her mouth, likely the result of surviving smallpox, and possibly due to the use of earlier "variolation" to induce immunity.
At the far right, the Junor Queen (also named Devajammani), unorthodoxly lifts her sari to reveal the site where the revolutionary new vaccine would be administered, silently endorsing and reassuring her subjects of the progress being made in western medicine. She would take the vaccine in July 1806.
The woman in the center is Lakshmi Ammani herself, the grandmother to the Maharaja of Mysore. A shrewd woman who had orchestrated the royal family's rise back to power through an alliance with the British, she actively promoted the smallpox vaccine as her husband had died from the disease.