u/Chumonka

▲ 1 r/dexcom

G7 10 day vs 15 day

I'm thinking about getting the 10 day (still on the G6). My thinking is that the failure rate is lower with the 10 day and you have more sensors (3 vs 2 per month to cover failures). The 15 day usually fails a few days early anyway. What do you think?

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u/Chumonka — 8 days ago
▲ 10 r/desmoid

New Drug Application for Varegacestat submitted to FDA

Varegacestat has announced promising results from the Ringside trial - 84% reduction in risk of progression and the objective response rate (tumor reduction) was 56% compared to 9% in the placebo group. It will take 6 to 12 months for the FDA to announce the results, depending on if it is granted priority review.

It is great news that we will have another treatment available for Desmoid tumors. The most commonly used treatments (after active surveillance) are nirogacestat, sorafenib, cryoablation, doxil.

https://www.targetedonc.com/view/new-drug-application-submitted-for-varegacestat-in-desmoid-tumors

Here is another recent review of desmoid tumor treatment and disease mechanisms. See figure 1 for a good visual on disease mechanisms and table 1 for a comparison of the treatments.

https://ascopubs.org/doi/10.1200/EDBK-26-520026?url_ver=Z39.88-2003&rfr_id=ori:

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u/Chumonka — 21 days ago