u/ComprehensiveRate953

I’ve been reading the new 2026 Mayo Clinic RLS management algorithm, and it looks like the recommendations for iron treatment have changed massively. They now say IV iron should be considered for any chronic RLS patient with ferritin 75–300 μg/L and TSAT <45%, and that people with ferritin 100–300 respond just as well as those below 100.

This is very different from the older UK/NICE approach, which usually only considers IV iron when ferritin is <100 and TSAT is very low.

Has anyone in the UK actually managed to get IV iron based on this newer evidence?
Did you go through neurology or haematology?
And is there anything specific you said or brought (e.g., the Mayo paper) that helped?

I’m trying to figure out what’s realistically possible within the NHS and whether anyone has had success getting IV iron for RLS with ferritin in the “normal” range.

Would really appreciate hearing your experiences.

Reference: An Updated Algorithm for the Management of Restless Legs Syndrome - Mayo Clinic Proceedings

Hi everyone,

I have CPTSD and OCD. Because of this, my brain constantly enters hyper-vigilant analysis loops whenever I experience a threatening, insulting, or manipulative situation. Lately, I've noticed a strange cognitive trap I'm stuck in.

Part of me feels like my OCD and constant over-analyzing is the exact mechanism that allowed me to get deep insights into my trauma and human behavior. Because I replay situations over and over, I spot the dynamics of how people treat me.

Now, I'm terrified that if I try to manage my OCD and stop the loops, I will rob myself of further insights and leave myself unprotected. I feel like stopping the analysis means letting my guard down.

Has anyone else reconciled this? How do you learn to trust that you can still be insightful and safe without relying on an exhausting OCD loop to do the work?

I've read endlessly that SSRIs will only make RLS worse. However, given the fact that there are very few alternatives, especially for anxiety, are many people on gabapentin/pregabalin in order to to mitigate their RLS symptoms while taking an SSRI? How is that working out for you? Would love to hear individual experiences.