Samwell Tarly's aunt is the Lady of Oldtown (Spoilers TWOW)
I never noticed this connection. Old Lord Leyton Hightower is currently married to Rhea Florent (his fourth wife). Rhea Florent is the older sister of Melessa Florent, who is married to Randyl Tarly. They have two sons, Samwell and Dickon Tarly. Sam never mentions his aunt Rhea possibly being in Oldtown where he is in AFFC. She only appears in the appendix
I've long had trouble imagining Samwell's arc in TWOW. He has so many magical variables: the glass candle; possibly the Horn of Joramun in his bag; a Faceless Man nearby; Lord Leyton Hightower "consulting spell books" with his daughter Malora the Mad Maid; and Euron Greyjoy nearby about to do a blood sacrifice for some unknown magic purpose. And there's a hundred non-magic factors. Now this bit about Sam's aunt Rhea Florent complicates Sam's precise trajectory even further, but it supports the idea that Sam will have a confrontation with his family and his past.
It also increases the likelihood (imo) that Sam will specifically have some kind of interaction with Lord Leyton and the Hightower. We may see the inside of the Hightower from a character POV for the first time. This, I predict