My current campaign is about a group of Aberrations deluding themselves to be Gods - without much understanding of what they are actually doing.
As such, my players have just met the (self-proclaimed) God of Nature sitting in a dark cave and using ancient magiteck to 3D-Print living spiders. It doesn't particularly care about the spiders, just found them the most resilient for its experiments (randomly sowing them together to see what happens) and its obsessed with making a big egg to rebirth itself so it can grow and eat its brothers. (The other aberrations)
Any efforts in convincing it that its idea of Nature is horrible have been futile. As such, my PCs have procured as many explosives as they could get their hands on. For obvious reasons.
So here is my invitation to you. Think of a mind about as stable as a Beholder, deciding it should take over one of those pesky divine domains.
And worst: succeeding.
Could be a fun exercise.