u/Dankleberry_Don

Enabling android auto on Scenic IV?

Hi all,

I've recently purchased a Renault scenic IV as my first car, and I'm loving it so far! I also found out that supposedly there is support for android auto, but this isn't something my particular model appears to have enabled as standard. However, I'm aware of a way to change it by using ddt4all, and an OBD-2 interface. My issue is most of the cheap ones I've found and tested either haven't worked at all, or work only in read-only mode. Does anyone have experience with a good quality adapter, and where I could get one and not get scammed from dodgy sellers on Amazon/eBay?

u/Dankleberry_Don — 7 hours ago

▲ 6 r/chemistry

Anyone versed in nucleotide synthesis?

Hi all,

I'm currently trying to phosphorylate a couple of nucleoside analogues, namely using the procedure in doi: 10.1002/cpz1.70169 . The basis of the reaction is to dissolve the NA in pyridine, then react with 4 equiv of POCl3, followed by a buffer workup to get the monophosphate. The initial stage of this reaction has failed every time so far for me, I've checked my regents don't contain water, let it run for longer than described, and still nada. Has anyone here tried this (or a similar) way of phosphorylating a nucleoside, and is aware of any common pitfalls. I am aware of another procedure of Yoshikawa that involves dissolving the nucleoside in an alkyl phosphate (TMP/TEP), but removing the residues of these (as well as the formed dimethyl phosphate) has proven quite difficult, so I'm trying to find a way that avoids using them altogether.

reddit.com

u/Dankleberry_Don — 2 months ago