The World Health Organization (WHO) reports a new case of infection in the hantavirus outbreak on the cruise ship Hondius. It involves a crew member who disembarked in Tenerife, was repatriated to the Netherlands, and has been in isolation since then, the WHO reports on X.

According to the WHO, twelve infections have now been confirmed. Three people have died. Since May 2, when the outbreak was first reported to the WHO, no new deaths have been recorded.

More than six hundred people in thirty countries are being monitored. In addition, health services are trying to track down a small number of people at high risk of infection.

The WHO calls on the countries involved to continue to closely monitor passengers and crew members during the remainder of the quarantine period.

If you have MCAS and POTS: did any meds or supplements that work on the MCAS/mast cells also help your POTS, like through synergy or even the POTS being partly secondary to the MCAS or something like that? Which ones & how? Any answers are welcome, also specifically wondering about various H1 antihistamines, H2 antihistamines, quercetin supplements, ketotifen, oral cromolyn, nasal cromolyn, or Singulair/montelukast?

In my experience H1 antihistamines and nasal cromolyn have definitely been somewhat helpful in partially reducing some aspects of POTS.

I wish everyone would stop making predictions about how this is going to go. We don’t know how this is going to go. A lot of us — including me — think everything is basically going to be okay from here on out, and that death and suffering will be limited. Yet a lot of us (including me) were DEAD WRONG on SARS-CoV2/COVID. So it’s fine if people say why they think everything will probably be okay, but a little uncertainty and humility would honestly be both more human AND more scientific.

I have been very concerned about global warming for decades but I NEVER thought modern scientific civilization would have a major deadly pandemic until I was sitting in my apartment in NYC day after day in March/April 2020 hearing the city silent besides ambulances while each day the death toll in the city rose by the 100s or 1000s until after 45 days into the pandemic there were 20,000 people dead of SARS-CoV2/COVID in NYC. My microbiologist spouse knew better, of course, LOL.

And I don’t want to hear ”there is no risk to the public.” What I want to hear is that the precautionary principle is being diligently followed in order to track, trace, test, monitor, isolate, quarantine as strictly as possible in order to nip any possibility of a larger outbreak in the bud. Getting the details of that is nice, if it’s possible, but just getting told over and over that that is happening and we will get through this is also fine.

LOL Andrew Cuomo is a bad guy in many, many ways but goddamn some of his daily televised/live-streamed video press conferences during the worst of the COVID pandemic and the lockdowns were friggin’ amazing and so reassuring at times. And he didn’t tell us “there is no risk to the public.” It may just be ”communications” but it matters.

A Canadian isolating in B.C. has presumptively tested positive for hantavirus after leaving the cruise ship affected by an outbreak of the Andes strain in recent weeks, B.C.'s top doctor said Saturday.

Dr. Bonnie Henry, provincial health officer, said Saturday the patient started to develop mild symptoms, including fever and headache, two days ago. The individual was taken to hospital in Victoria, and assessed and tested there.

The BC Centre for Disease Control confirmed a presumptive positive test result on Friday. It will need to be confirmed by a microbiology lab in Winnipeg. The person is still in hospital in isolation and considered stable. [...]

I am male and near 50 and was diagnosed with suspected-post-COVID POTS/dysautonomia 5 years ago back towards the height of the pandemic in my early 40s based on history and copious self-gathered data and ruling out other possibilities with an echocardiogram, an EKG, an EKG stress test, and an echo stress test. I have never had a proper tilt table test.

I have some positional/orthostatic mild light-headedness, and a lot of other on and off issues I think relate to this, with the biggest being left upper chest pain, but really my biggest problematic symptoms are a mix of positional/orthostatic 1) overwhelm/irritation/edginess/anxiety; 2) weakness/tiredness/fatigue.

Recently #1, agitation etc., is by far a bigger issue than weakness/fatigue, but it goes away when I lie down entirely pretty fast, and also when I sit — there’s no general anxiety as long as my body is in those positions, and the triggers aren’t psychological ones for the anxiety like aspect and I don’t have anything of the more psychological components of an anxiety disorder — only the physiological ones and only when I stand mostly.

The problem is I need some management for this pharmaceutically and my experiences are only with beta blockers and midodrine, and neither works as well as I’d like (and midodrine I don’t think works at all for this, it helps more with weakness/fatigue).

I have a low end of normal pulse generally at rest, and my pulse rise is low end of POTS requirements. I don’t seem to have hyperadrenergic-type BP issues as I have a consistent BP change that clearly, and the degree there is a change it’s an isolated rise in diastolic BP only.

I’ve never had a tilt table test or any kind of testing of norephinephrine levels but I suspect that’s some kind of issue here from this hyped up fearful/irritated thing I get.

I’ve been discussing a possible future change in meds with my doctor including trying ivabradine — but I’m wondering if ivabradine will help with positional agitation/irritation-type symptoms? Esp. as my pulse isn’t that high at all. Or is there any other meds I should discuss with doctor? I mentioned clonidine but they were hesitant since my BP isn’t high.

As far as non-pharmaceutical things I have no experiences with any really helping this agitation/irritability/fear/panic physiological stuff. I have good experiences with compression socks for weakness/tiredness but they do nothing for the agitation/overwhelm/irritation/edginess.

Due to upper and lower chronic GI issues and how I react to electrolytes in ANY form there is no way for me to get them in at anything but very minor token levels consistently. I tend to drink a lot of water and many of my electrolyte levels on blood tests are at very low end of normal. I’ve been wondering if I should discuss fludrocortisone with doctor for this reason. But the real issues is the anxiety/irritation/agitation….

EDIT: I figured it out, this report just lists them as VE, or ventricular ectopics

I apologize if I am completely not understanding how this works — I probably am!

I just got back a provisional version of the 15 page report on my 7 day monitor, I believe not reviewed by my doctor yet (not sure on that) and will be discussing with cardiologist early next week.

Overall it was good and healthy and relieving, but I thought it might say something about my PVC burden overall but don’t see that obviously — probably that means it’s insignificant? Some of the manual events listed involve PVCs and bigeminal PVCs it says but not the majority, and that’s about it.

I’m assuming not seeing anything means it’s good but would love it if it said like “insignificant PVC burden overall” etc. so just want to know how to understand this to be most relieved and then maybe move on to assuming my various weird painful chest sensations are musculoskeletal or GI or due to my known autonomic nervous system dysfunction (which does often cause tachycardia and sometimes bradycardia), but nothing dangerous involving my heart….honestly if I hadn’t had a parent die very suddenly about my age of undiagnosed and somewhat unclear heart disease issues wouldn’t even be on my mind with my recent sudden major uptick of weird chest pains LOL..

I've seen it suggested/hypothesized elsewhere on REddit-- based on zero evidence except that this current outbreak was on a cruise ship with a lot of older people -- that maybe ANDV will only or disproportionately cause severe illness or death in older people. I guess this is supposed to "reassure" young people LOL (as someone who is near 50 and most people I know are my age or older, it doesn't reassure me LOL). Anyway while there is a lot we do not yet know, from my brief research not only is there zero evidence of such an age pattern of severity overall for ANDV or other hantaviruses generally, but according to this article on the Epuyen outbreak in 2018-2019, the 1st death was a 14-year-old girl. This is a horrible tragic disease and hopefully it's contained or there's going to be a lot of death and suffering....

A quinceañera party, 34 infected and 12 dead: Argentina's biggest hantavirus outbreak provides clues for the MV Hondius case

I had an echo stress test in 2021 and the results state that "The left ventricular cavity size became smaller with stress.” Is that a normal finding? Nobody even mentioned it to me at the time so I assume it’s normal and healthy but just checking. The test results were negative for ischemia with no abnormal wall motion noted.

What can an ECG stress test show that a 7-day-monitor can’t? Specifically a BodyGuardian Mini Plus montior.

There’s a fact about current COVID vaccine technology effectiveness that got memory-holed by society as a whole and I think there is some confusion about it even among some people on this sub, perhaps because they were so young back in 2021, I don’t know. But people are telling me I’m misrepresenting when I say that I’ve been hearing that a “sterlizing vaccine is just around the corner” since SARS-CoV2 came on the scene…and I am not.

So part of the reason many of us, especially those of us who are CC and older, are cynical about the possibility of a “sterilizing vaccine” for SARS-CoV2 is that they we remember that during the development of the current MRNA COVID vaccine technologies in 2020 and their deployment in 2021 that we were told that they would prevent most infections with the virus based on the research done after their development and before their release. This was what the companies who made them said, what the scientific journals said, what the government officials said, what the news media said, what the public health officials said. There was even a term for the supposedly rare infections people would get after vaccination — a “breakthrough infection,” which again were supposed to be rare.

This pretty quickly turned out to not be the truth at all due to the rapid evolution of the virus, and was certainly clear by the time of the first global Omicron wave at the end of 2021 and start of 2022 — I’m not sure if breakthrough infections were common with the very deadly Delta wave in the USA in summer 2021 or if that was more of an issue in red state areas with low vaccine uptake due it being so politicized here. But by 2022 the government and the news media and the public health authorities and the corporations making vaccines had SUDDENLY STOPPED saying the vaccines prevented almost all infections— and they never really admitted this.

But since the MRNA COVID vaccine technologies failed to effectively stop infection even in those who received them due to the virus’s rapid mutation, basically those of us who were COVID Cautious/Zero-COVID-minded have been hearing from some portion of science and public health related people that a truly sterilizing vaccine, or at least way more effective technology, was right around the corner. We’ve been waiting on this since that Omicron wave in late 2021/early 2022. It hasn’t come. Maybe it will some day, maybe it won’t, but a lot of us are cynical because we have followed these things from the start. Just to be clear.

And to add: I don’t know the history of Novavax and how that fits in but I don’t think anyone has ever credibly argued it was more than marginally more effective at preventing infection than the MRNA technologies, though it is the only vaccine I get any more since some side effect issues with MRNA I had — but if I had no choice I’d still get MRNA.

Oh and to add further, it was the fact that the vaccines were supposed to prevent most infections that was a big part of why there were all those controversial vaccine mandates…the mandates were supposed to potentially save the lives of those getting the vaccines as well as those they would pass it on to...

Science question here, if as this comment at below link says, Invivyd mAb VYD2311 (which is being tested NOW) won’t come out until fall 2027 or even fall 2028, why would the technology still work, or at least work as effectively, on whatever variants of SARS-CoV2 that are still circulating any where from 1.25 to 2.25 years from now?

https://www.reddit.com/r/ZeroCovidCommunity/comments/1sgmyvs/comment/ofgbx0f/

Yeah so I’m wondering the opinions of people on here about whether the dangers of SARS-CoV2 will be significantly reduced in the next 5 to 10 years? And then so to what degree do you think it will improve — will we be able to stop wearing N95s in public at all times etc.? And why will it improve ie. through what changes in technology, politics, or culture?