u/DolunddTrump

My father (66M) was diagnosed with metastatic hormone-sensitive prostate cancer 2 months ago and we’re stuck in a situation where every oncologist we consult gives a different opinion on chemotherapy. Looking for real experiences from patients or caregivers who faced this same decision.

His diagnosis:
Gleason 4+5 = 9 (Grade Group 5), de novo presentation (metastatic at first diagnosis)

PSA at diagnosis: 251

PSMA PET-CT: PSMA avid left common iliac and external iliac lymph nodes. PSMA avid sclerotic and marrow-based lesions involving lower lumbar vertebrae, sacrum, and left iliac bone.
No visceral involvement (lungs, liver, brain all clear)

By CHAARTED criteria — this is LOW VOLUME disease (3 bone lesions, no visceral mets)

Current treatment (started June 2026):
ADT(degarelix) + ARPI(abirateron)

4 doctors have said no chemo required in Low Volume cases, 3 Doctors are very keen on chemo saying to strike hard as early as possible

In a huge dilemma of whether to proceed with chemo or not. Please guide!

Marketplace will be filled with AI slop or the demand’s are gonna hit an all time low

Marketplace will be filled with AI slop or the demand’s are gonna hit an all time low

I’m working on an anonymous review flow where users rate first and then write likes/dislikes.

The challenge:
Increase the number of users who write
Increase review quality/length
Keep the experience lightweight and fun
Cannot compromise anonymity

What are some clever patterns you’ve seen work beyond generic progress bars and character counters?

I did my bachelors in Computer Science but i transitioned in UX in 2022, got my 1st job in 22 and switch to my present job in late 2024

I hate this decision!!!

A developer works for 4 hours, his work his done, he’s free for the rest of the day

But a designer works for 4 hours, his work won’t be considered complete until the manager likes it.

Dude my dad is battling cancer, and these mfs want me to come up with “cool and innovative genz” ideas and that too in prototype coz now we have AI, fkin retards!!!!!!

I work here for the whole day to come up with “cool and innovative” ideas but that mf manager comes and says these might not work and i have to work all over again and bring some more ideas

Dude everytime my team acts like they’re some artists or whatnot, and they say stuff like everything has a story, bring story in features,
what storyyyyyyyy in featureessss???!!!!!

Dude i spent the whole day working from home for this mf and its just went into vain, i could’ve spent more time with my dad, i don’t know how many days are left and that mf manager had the audacity to ask when i am coming back to office.

I am so so so stuckkkk,
\- i dont have time to switch jobs
\- I can’t stay home with my dad coz my company is calling me in office
\- I can’t leave my job as i have to support financially
\- and i hate what i do for my work

I HATE THE FACT THAT I HAVE TO DO SOMETHING WHICH I HATE JUST TO SUPPORT MY FAMILY STAYING AWAY FROM MY DAD

I did my bachelors in Computer Science but i transitioned in UX in 2022, got my 1st job in 22 and switch to my present job in late 2024

I hate this decision!!!

A developer works for 4 hours, his work his done, he’s free for the rest of the day

But a designer works for 4 hours, his work won’t be considered complete until the manager likes it.

Dude my dad is battling cancer, and these mfs want me to come up with “cool and innovative genz” ideas and that too in prototype coz now we have AI, fkin retards!!!!!!

I work here for the whole day to come up with “cool and innovative” ideas but that mf manager comes and says these might not work and i have to work all over again and bring some more ideas

Dude everytime my team acts like they’re some artists or whatnot, and they say stuff like everything has a story, bring story in features,
what storyyyyyyyy in featureessss???!!!!!

Dude i spent the whole day working from home for this mf and its just went into vain, i could’ve spent more time with my dad, i don’t know how many days are left and that mf manager had the audacity to ask when i am coming back to office.

I am so so so stuckkkk,
\- i dont have time to switch jobs
\- I can’t stay home with my dad coz my company is calling me in office
\- I can’t leave my job as i have to support financially
\- and i hate what i do for my work

I HATE THE FACT THAT I HAVE TO DO SOMETHING WHICH I HATE JUST TO SUPPORT MY FAMILY STAYING AWAY FROM MY DAD

I did my bachelors in Computer Science but i transitioned in UX in 2022, got my 1st job in 22 and switch to my present job in late 2024

I hate this decision!!!

A developer works for 4 hours, his work his done, he’s free for the rest of the day

But a designer works for 4 hours, his work won’t be considered complete until the manager likes it.

Dude my dad is battling cancer, and these mfs want me to come up with “cool and innovative genz” ideas and that too in prototype coz now we have AI, fkin retards!!!!!!

I work here for the whole day to come up with “cool and innovative” ideas but that mf manager comes and says these might not work and i have to work all over again and bring some more ideas

Dude everytime my team acts like they’re some artists or whatnot, and they say stuff like everything has a story, bring story in features,
what storyyyyyyyy in featureessss???!!!!!

Dude i spent the whole day working from home for this mf and its just went into vain, i could’ve spent more time with my dad, i don’t know how many days are left and that mf manager had the audacity to ask when i am coming back to office.

I am so so so stuckkkk,
- i dont have time to switch jobs
- I can’t stay home with my dad coz my company is calling me in office
- I can’t leave my job as i have to support financially
- and i hate what i do for my work

I HATE THE FACT THAT I HAVE TO DO SOMETHING WHICH I HATE JUST TO SUPPORT MY FAMILY STAYING AWAY FROM MY DAD

We as a family are in a really big dilemma right now

Abirateron has side effects which can increase bp, cholesterol and sugar

My father (66) has BP, takes regular medicine for it, has cholesterol and is pre-diabetic
Plus a steroid must be taken with it

Darolutamide on the other hand increases none of that,
But is really really expensive, insurance doesn’t cover it

What should we do? Does abirateron increases the chances of heart attack?

I live away from my parents for my job so is this is the case then it would be really concerning for us

We as a family are in a really big dilemma right now

Abirateron has side effects which can increase bp, cholesterol and sugar

My father (66) has BP, takes regular medicine for it, has cholesterol and is pre-diabetic
Plus a steroid must be taken with it

Degarelix on the other hand increases none of that,
But is really really expensive, insurance doesn’t cover it

What should we do? Does abirateron increases the chances of heart attack?

I live away from my parents for my job so is this is the case then it would be really concerning for us

Doctor gave 2-2.5 years to my father before even the treatment started. We have 2nd thoughts now to get the treatment from someone who is this negative

My father has a psa of 220 and gleason score of 9.

Metastatic case with 4 sites effected with no organs affected

I am still not able to process why would he give such less life expectancy? Is gleason score 9 that serious?

Also he was forcing to operate the testicles but we do have the choice of injections

Two days back my father’s biopsy reports came and the gleason score was (4+5) 9,and they are saying that once it has metastasised to bones, radiation is out of consideration and they are considering chemo now.

With a PSA of 240 and only 3 sites metastasised (left pelvic, lower vertebrae and a lymph node)

But this is totally opposite to what i have been studying till now, i was of the view that we’ll start with adt + radiation therapy. What should i do now

Dad recently git diagnosed with stage 4 prostate cancer, i need this book in the pdf form so that i can give it to AI and ask personalised questions

My father 64, has a psa of 250, and in the per scans we found it was on the left pelvic bone, the lower vertebrae and a lymph node

Basically an oligometastatic case, we are awaiting the result of biopsy, what sort of gleason score can we expect it to be?

Yes, i know research about a niche, but yeah then what??

My father’s treatment start probably in 2 weeks from now, it will be ADT, i am really scared of kind of side effects he has to go through

Are they for life? Will they ever stop?

My father overthinks a lot so i am really scared because of that

Please guide me how can i make him live a normal lifestyle

My father’s treatment start probably in 2 weeks from now, it will be ADT, i am really scared of kind of side effects he has to go through

Are they for life? Will they ever stop?

My father overthinks a lot so i am really scared because of that

Only 3 bones/lymph nodes affected, is it a good sign?

- Is it still stage 4?

- Since the spread is in less than 4 bones is it curable?

- can we expect a long life expectancy?

No other bone or soft organ is affected as of yet. Is a good sign? That the cancer hasn’t spread widely and the treatment will only reduce it from here.

How many years can i expect for my dad? He is 67