u/Early-Bit-8277

Severe depression - 125mg Spironolactone for 8+ months

Hi there, I'm 39 year old female and have been dealing with chronic skin issues (acne and perioral dermatitis) for over 4 years, i finally caved and started taking Spiro in October, I would say that within a month I noticed lower mood, but really wanted my skin to clear up and didn't think it was too bad, but over the last 9 months it has been a slow but steady decline with my mental health, culminating in this last week where I felt suicidal. I started seeing all of these posts about perimenopause and in addition to extremely low mood, and irritability, I also feel like I can't remember anything and have joint aches. I went to see my dr and she said that I have low ferritin (24) and that although rare Spiro can have side effects of depression and confusion/brain fog, so before she explores anything like HRT she wants to see how I feel off of spiro and then maybe put me on Wellbutrin. She says that if my other perimenopause symptoms persist (brain fog, irritability, joint aches, night sweats) then she will look at HRT for me. Has this happened to anyone else - specifically severe depression from being on spiro??

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u/Early-Bit-8277 — 2 days ago