u/Electrical-Weather88

I'm studying the Ilizarov method and wondering if it's possible to do something similar without surgery, using microfractures and traction. I know it's controversial, but I wanted to exchange ideas about the mechanics. Has anyone here researched this?

It's a project I suddenly became curious about. but I have no idea how to execute this conceptual project, since I'm an amateur. So, I wanted opinions from professionals Or people who understand the subject.

Guys, I'm working on a height growth protocol after puberty, aimed at people who want to aesthetically increase their height, and I'll possibly adapt it for athletes. But overall, using purely mathematical methods and assumptions about biology, it's possible to grow up to 10cm per year. Do you want me to post the project concept here?

Recently, I have been developing a project that innovates in the niche of tissue manipulation, especially skeletal bones, with the aim of treating people with dwarfism and gigantism, Or simply for aesthetic purposes. I saw in a study that stem cells can be fundamental to the development of this project, so I came to this Reddit subreddit to ask if the community Do you know anything about this? Can anyone offer an opinion on the matter, or could a professional analyze it?

Hi everyone,

I've been developing (as a thought experiment / early research concept) a project called HÉLIX — a non-invasive system for longitudinal bone growth in adolescents (potentiation) and potentially adults (recreating functional growth plate-like tissue). Core idea: Instead of trying to build a "perfect" growth plate, create an imperfect but smart, zonated artificial one that is continuously corrected via feedback. Main modules: EXO: Wearable exoskeleton with controlled axial traction, mechanical pulses, sensors (strain, alignment) + AI for real-time adjustments. BIO: Zoned hydrogel scaffold (GelMA/alginate/hyaluronic acid + nano-HA) implanted or injected at the former epiphyseal plate region. MSCs or chondrocytes + hypoxia-mimicking environment initially. Controlled Release: PLGA microspheres or stimuli-responsive systems for temporal/spatial delivery of PTHrP (to delay hypertrophy), IGF-1/TGF-β3 (proliferation), and later BMPs/VEGF (controlled ossification). Feedback loop: Sensors + IA adjust traction, factor release and possibly piezoelectric stimulation to maintain proliferative zone, prevent premature bone bridging and asymmetry. This draws heavily from current literature on growth plate tissue engineering (zoned hydrogels, PTHrP-loaded PLGA in GelMA scaffolds, Ihh-PTHrP loop, hypoxia for chondrogenesis, etc.). Main challenges I'm aware of: Long-term maintenance of cartilaginous phenotype. Controlled vascularization without early ossification. Integration with mature bone in adults. Safety (asymmetry, tumors, immune response). What do you think? Has anyone seen similar integrated approaches (mechano + controlled release + closed-loop)? Any papers, labs or critical flaws I should consider before going deeper? Thanks in advance! Open to collaboration/feedback.

Hi everyone,

I've been developing (as a thought experiment / early research concept) a project called HÉLIX — a non-invasive system for longitudinal bone growth in adolescents (potentiation) and potentially adults (recreating functional growth plate-like tissue). Core idea: Instead of trying to build a "perfect" growth plate, create an imperfect but smart, zonated artificial one that is continuously corrected via feedback. Main modules: EXO: Wearable exoskeleton with controlled axial traction, mechanical pulses, sensors (strain, alignment) + AI for real-time adjustments. BIO: Zoned hydrogel scaffold (GelMA/alginate/hyaluronic acid + nano-HA) implanted or injected at the former epiphyseal plate region. MSCs or chondrocytes + hypoxia-mimicking environment initially. Controlled Release: PLGA microspheres or stimuli-responsive systems for temporal/spatial delivery of PTHrP (to delay hypertrophy), IGF-1/TGF-β3 (proliferation), and later BMPs/VEGF (controlled ossification). Feedback loop: Sensors + IA adjust traction, factor release and possibly piezoelectric stimulation to maintain proliferative zone, prevent premature bone bridging and asymmetry. This draws heavily from current literature on growth plate tissue engineering (zoned hydrogels, PTHrP-loaded PLGA in GelMA scaffolds, Ihh-PTHrP loop, hypoxia for chondrogenesis, etc.). Main challenges I'm aware of: Long-term maintenance of cartilaginous phenotype. Controlled vascularization without early ossification. Integration with mature bone in adults. Safety (asymmetry, tumors, immune response). What do you think? Has anyone seen similar integrated approaches (mechano + controlled release + closed-loop)? Any papers, labs or critical flaws I should consider before going deeper? Thanks in advance! Open to collaboration/feedback.